This paper contributes to the development of evolutionary machine learning (EML) for optimal polar-space fuzzy control of cyber-physical Mecanum vehicles using the flower pollination algorithm (FPA). The metaheuristic FPA is utilized to design optimal fuzzy systems, called FPA-fuzzy. In this hybrid computation, both the fuzzy structure and the number of IF–THEN rules are optimized through the FPA evolutionary process. This approach overcomes the drawback of the structure tuning problem in conventional fuzzy systems. After deriving the polar-space kinematics model of Mecanum vehicles, an optimal EML FPA-fuzzy online control scheme is synthesized, and the global stability is proven via Lyapunov theory. An embedded cyber-physical robotic system is then constructed using the typical 5C strategy. The proposed FPA-fuzzy computation collaborates with the advanced sensors and actuators of Mecanum vehicles to design a cyber-physical robotic system. Compared with conventional Cartesian-space control methods, the proposed EML FPA-fuzzy has the advantages of metaheuristics, fuzzy online control, and cyber-physical system design in polar coordinates. Finally, the mechatronic design and experimental setup of a Mecanum vehicle cyber-physical system is constructed. Through experimental results and comparative works, the effectiveness and merit of the proposed methods are validated. The proposed EML FPA-fuzzy control approach has theoretical and practice significance in terms of its real-time capability, online parameter tuning, convergent behavior, and hybrid artificial intelligence.