Embedded device for simultaneous recording and stimulation for retina implant research

Schloesser, Mario; Cota, Oscar; Heil, R.; Brusius, Janis Sebastian; Offenhäusser, Andreas; Waasen, S. van; Schiek, M.

doi:10.1109/icsens.2013.6688173

Cited by 8 publications

(4 citation statements)

References 4 publications

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“…Using this bidirectional enhancement system, it is possible to characterize response types from specific retinal areas and to modify stimulation algorithms to accommodate intrinsic activity of retinal neurons and thereby deliver more effective stimulation patterns. 38,41…”

Section: Epiretinal Prosthesesmentioning

confidence: 99%

Advances in retinal prosthesis systems

2019

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Retinal prosthesis systems have undergone significant advances in the past quarter century, resulting in the development of several different novel surgical and engineering approaches. Encouraging results have demonstrated partial visual restoration, with improvement in both coarse objective function and performance of everyday tasks. To date, four systems have received marketing approval for use in Europe or the United States, with numerous others undergoing preclinical and clinical evaluation, reflecting the established safety profile of these devices for chronic implantation. This progress represents the first notion that the field of visual restorative medicine could offer blind patients a hope of real and measurable benefit. However, there are numerous complex engineering and biophysical obstacles still to be overcome, to reconcile the gap that remains between artificial and natural vision. Current developments in the form of enhanced image processing algorithms and data transfer approaches, combined with emerging nanofabrication and conductive polymerization techniques, herald an exciting and innovative future for retinal prosthetics. This review provides an update of retinal prosthetic systems currently undergoing development and clinical trials while also addressing future challenges in the field, such as the assessment of functional outcomes in ultra-low vision and strategies for tackling existing hardware and software constraints.

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Section: Epiretinal Prosthesesmentioning

confidence: 99%

Advances in retinal prosthesis systems

2019

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“…With a short OpAmp settling time of less than a microsecond it is possible to further investigate the immediate neuronal response (Fig.5). Thus we gained a reliable system to enable next generation retina implant research [8].…”

Section: Recording and Stimulation For Retina Implant Researchmentioning

confidence: 99%

Automated electrical stimulation and recording for retina implant research by LabVIEW configured standalone data acquisition device

Heil

Schloesser

Offenhäusser

et al. 2014

2014 Proceedings of the SICE Annual Conference (SICE)

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To understand the neural processes within retina cell layers recent retina implant research focusses on bidirectional communication with bi-polar and ganglion cells in in-vitro retinal tissue. In order to enable this research we had developed a front-end to stimulate and record retinal cell layers with a slight time gap only and thus avoiding long recording dead times. To ease experiments with this front-end, we developed a versatile and user optimized embedded data acquisition device, named iNODE5. This can be configured using a LabVIEW based graphical user interface. We adapted the front-end to the form factor of the commercial measurement device USB-6009OEM from National Instruments. Now, for evaluation and parameter testing the front-end can be plugged into the National Instruments board and controlled via a graphical user interface which enables the export of the basic configuration parameters for later automated standalone measurement and stimulation. For this the front-end is attached to the iNODE5 which reads the experiment configuration from the personal computer via USB or SD-card. The automated electrical stimulation and recording can be started or stopped by a terminal program or a button placed on the iNODE5.

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“…In addition, this system has a bi-directional enhancement system, which allows for simultaneous stimulation of and recording from the microelectrodes. Feedback from the system enables modification of the stimulation algorithms and patterns to accommodate any residual excitatory and inhibitory signal processing of the retinal neurons [49,50]. The Argus II Retinal Prosthesis System DOI: http://dx.doi.org/10.5772/intechopen.84947…”

Section: Data and Power Transmissionmentioning

confidence: 99%

The Argus II Retinal Prosthesis System

Bloch¹,

Cruz²

2020

Prosthesis

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The field of retinal prosthetics has seen significant advances in the past 3 decades. Encouraging results from different groups have shown coarse objective functional improvement, using a range of technological and surgical approaches. The Argus II retinal prosthesis system was the first of its kind to receive regulatory approval for commercial use in Europe and the USA. The device is designed to replicate the function of photoreceptors in converting visual information into electrical neural signals in patients with profound visual loss secondary to degenerative retinal disease. Results from a phase II study of 30 patients have demonstrated improved performance in basic tests of visual function, object recognition, letter reading, prehension, orientation and mobility tasks. It is now the most widely implanted retinal prosthetic device worldwide. This chapter provides an overview of the requirements of a retinal prosthetic system, the results from the Argus II device to date, and an insight into some of the challenges and future directions of visually restorative therapies.

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Embedded device for simultaneous recording and stimulation for retina implant research

Cited by 8 publications

References 4 publications

Advances in retinal prosthesis systems

Advances in retinal prosthesis systems

Automated electrical stimulation and recording for retina implant research by LabVIEW configured standalone data acquisition device

The Argus II Retinal Prosthesis System

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