Emergence of
 mcr-1
 in Raoultella ornithinolytica and Escherichia coli Isolates from Retail Vegetables in China

Luo, Jun; Yao, Xu; Lv, Luchao; Doi, Yohei; Huang, Xiuyu; Huang, Sixiu; Liu, Jian Hua

doi:10.1128/aac.01139-17

Cited by 62 publications

(53 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…58,59 The mcr gene has rarely been isolated in R. ornithinolytica strains, with the first cases being found in retail vegetables in China. 60 Furthermore, emergence of mcr-8 gene and variant was also identified in R. ornithinolytica which raised concern about its co-transferability with other beta-lactamase genes. 58,61…”

Section: Virulence and Resistancementioning

confidence: 99%

Raoultella ornithinolytica: Emergence and Resistance

Hajjar¹,

Ambaraghassi²,

Sebajang³

et al. 2020

IDR

View full text Add to dashboard Cite

Raoultella ornithinolytica is an encapsulated Gram-negative, oxidase-negative, catalase-positive, aerobic, non-motile rod that belongs to the Enterobacteriaceae family. This bacterium was initially classified in the genus Klebsiella as Klebsiella ornithinolytica, until the creation of the genus Raoultella in 2001. R. ornithinolytica is usually found in water environments and soil, and due to its ability to convert histidine to histamine, it has been associated with histamine poisoning in humans. R. ornithinolytica is an emerging entity in human infections, with several reports of virulent infections in comorbid at-risk patients. Increasing reports are potentially due to better and more precise identification tools. The objective of this article is to provide a comprehensive review of reported cases of R. ornithinolytica infections, the emergent virulence of described multiresistant strains, and an overview of currently used identification methods.

show abstract

Section: Virulence and Resistancementioning

confidence: 99%

Raoultella ornithinolytica: Emergence and Resistance

Hajjar¹,

Ambaraghassi²,

Sebajang³

et al. 2020

IDR

View full text Add to dashboard Cite

show abstract

“…It has been described in numerous genera of Enterobacteriaceae including Escherichia, Moraxella, Klebsiella, Salmonella, Enterobacter, Cronobacter, Shigella, Kluyvera, Citrobacter, and Raoultella (Campos et al, 2016;Liu B.-T. et al, 2016;Liu Y.-Y. et al, 2016;Olaitan et al, 2016;Pham Thanh et al, 2016;Stoesser et al, 2016a;Zeng et al, 2016;Zhao and Zong, 2016;AbuOun et al, 2017;Li et al, 2017c;Luo et al, 2017). Although mcr genes have been found in a large diversity of clones, Matamoros et al (2017) and García-Meniño et al (2019) established the ST10 and ST155 E. coli clones as potential reservoirs of the mcr-1 gene.…”

Section: Introductionmentioning

confidence: 99%

Whole Genome Sequencing and Characteristics of mcr-1–Harboring Plasmids of Porcine Escherichia coli Isolates Belonging to the High-Risk Clone O25b:H4-ST131 Clade B

et al. 2020

View full text Add to dashboard Cite

“…Since Salmonella species harboring mcr‐1 were initially reported in 2016 in United Kingdom,15 the detection, escalation, and dissemination of mcr‐1 gene in Salmonella from food animals, humans, and environment is increasing worldwide. So far, mcr‐1 has been found in various S. enterica serotypes, such as Typhimurium, Enteritidis, Paratyphi B, Derby, Rissen, Virchow, Indiana, and London 16–21. New serotypes of Salmonella species carrying mcr‐1 continue to be discovered.…”

Section: Introductionmentioning

confidence: 99%

Carriage of Distinct mcr‐1‐Harboring Plasmids by Unusual Serotypes of Salmonella

et al. 2020

View full text Add to dashboard Cite

Colistin acts as a last‐resort antibiotic against lethal infections by carbapenem‐resistant Enterobacterial pathogens. Enterobacteriaceae carrying mobile colistin resistance (MCR) genes are rapidly emerging and threatening human health and food safety. Despite mcr‐1 being prevalent in Escherichia coli, its dissemination in Salmonella is not well characterized. Herein, two unusual serotypes of colistin‐resistant Salmonella isolates are reported first, namely serotype Ngor (ST5399) and Goldcoast (ST2529). Using whole genome sequencing, it is shown that mcr‐1 is located on the IncHI2‐like plasmid pTB501 (188,527 bp) of strain SSDFZ54 and the IncX4‐type plasmid pTB602 (33,303 bp) in strain SSDFZ69, respectively. Furthermore, the backbone, tra‐ and antimicrobial resistance genes relative variable regions in the mcr‐1‐bearing IncHI2 plasmids are systematically characterized. Phylogenetic analysis shows that all IncHI2‐type plasmids from non‐Chinese regions are clustered together, suggesting a possible Chinese origin. Taken together, these findings extend the understanding of Salmonella as a vehicle of mcr‐1 carriage and distribution.

show abstract

Emergence of mcr-1 in Raoultella ornithinolytica and Escherichia coli Isolates from Retail Vegetables in China

Cited by 62 publications

References 18 publications

<p><em>Raoultella ornithinolytica</em>: Emergence and Resistance</p>

<p><em>Raoultella ornithinolytica</em>: Emergence and Resistance</p>

Whole Genome Sequencing and Characteristics of mcr-1–Harboring Plasmids of Porcine Escherichia coli Isolates Belonging to the High-Risk Clone O25b:H4-ST131 Clade B

Carriage of Distinct mcr‐1‐Harboring Plasmids by Unusual Serotypes of Salmonella

Contact Info

Product

Resources

About