Endogene bakterielle Endophthalmitis: eine retrospektive Studie an 22 konsekutiven Fällen

Laube, Thomas; Akgül, Harun; Brockmann, Claudia; Höck, Kerstin; Schüler, Andreas; Bornfeld, Norbert; Schilling, Hannah

doi:10.1055/s-2004-812848

Cited by 8 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It usually affects people with immune deficiency, such as diabetes mellitus, renal failure, AIDS, malignancies, as well as immunosuppressive treatment, intravenous drug use and invasive surgery 2. Case series in the literature have reported 90% of patients with endogenous bacterial endophthalmitis (EBE) to have severe predisposing disorders, but the condition can also occur in apparently healthy individuals 2,3. The gold standard for identification of causative organism is positive culture.…”

Section: Introductionmentioning

confidence: 99%

Severe Acute Endogenous Endophthalmitis with Staphylococcus Epidermidis in a Systemically Well Patient

Whist¹,

Hollenbach²,

Dunlop³

2011

Ophthalmol Eye Dis

View full text Add to dashboard Cite

Endogenous endophthalmitis is a devastating intraocular infection caused by haematogenous spread of bacteria or fungi, usually in people with immune deficiency. This case report is unusual as a systemically well patient with normal immune function and no identifiable locus of infection rapidly developed a fulminant endogenous endophthalmitis from an organism which does not usually produce aggressive virulence determinants. Endogenous bacterial endophthalmitis is an ongoing diagnostic and therapeutic dilemma for ophthalmologists as it is relatively rare, often initially presents as uveitis, and requires a high index of suspicion for prompt diagnosis and treatment. The treatment of endogenous endophthalmitis is still controversial due to a lack of clinical trials. Potential treatments include systemic antibiotics, peri-ocular injections, intravitreal injection of antibiotics and possibly corticosteroids, pars plana vitrectomy, or a combination of some of these.

show abstract

Section: Introductionmentioning

confidence: 99%

Severe Acute Endogenous Endophthalmitis with Staphylococcus Epidermidis in a Systemically Well Patient

Whist¹,

Hollenbach²,

Dunlop³

2011

Ophthalmol Eye Dis

View full text Add to dashboard Cite

show abstract

Endogene Endophthalmitis

2007

View full text Add to dashboard Cite

Identification of endogenous endophthalmitis at an early stage with immediate initiation of therapy has significant implications for the further course of the disease. If--as in the present study--advanced cases are present with complicating internal or surgical disease and no possibility of short-term follow-up, pars plana vitrectomy should be given priority over single intravitreal injections. Major comparative investigations are desirable regarding the most appropriate method of endotamponade. Highlighting this clinical pattern more widely in non-ophthalmological specialties (e.g. intensive care, surgery) might decrease the rate of adverse outcomes associated with this disease.

show abstract

Endogene Endophthalmitis

Neß¹

2007

Ophthalmologe

View full text Add to dashboard Cite

Endogenous endophthalmitis is a severe and potentially blinding complication of hematogenous spread of microorganisms. Predisposing factors are intravenous drug abuse, immunosuppression, and prolonged intensive care. Intraocular material needs to be cultured or subjected to PCR to detect the causative microorganisms. In contrast to PCR, culture has the advantage of providing additional information about the resistance of the microorganism. Fungi and bacteria cause endogenous endophthalmitis with the same frequency. Treatment consists in a combination of local and systemic antibiotics or antimycotics, systemic and local corticosteroids, and vitrectomy. The prognosis depends mainly on the initial visual acuity and the pathogen concerned.

show abstract

Endogene bakterielle Endophthalmitis: eine retrospektive Studie an 22 konsekutiven Fällen

Abstract: Immediate diagnosis and therapy are crucial for a positive outcome in this ophthalmological emergency. Immediate pars plana vitrectomy with intraocular antibiotic instillation seems to improve the prognosis of the affected eyes.

Cited by 8 publications

References 9 publications

Severe Acute Endogenous Endophthalmitis with Staphylococcus Epidermidis in a Systemically Well Patient

Severe Acute Endogenous Endophthalmitis with Staphylococcus Epidermidis in a Systemically Well Patient

Endogene Endophthalmitis

Endogene Endophthalmitis

Contact Info

Product

Resources

About