Endometrial clear cell carcinoma metastatic to the paranasal sinuses: a case report and review of the literature

İlvan, Şennur; Akyıldız, Elif Ülker; Calay, Zerrin; Celikoyar, Mazhar; Şahinler, İsmet

doi:10.1016/j.ygyno.2004.04.005

Cited by 21 publications

(12 citation statements)

References 9 publications

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“…Therefore, incidence of bone metastases in clear cell endometrial carcinoma could be higher than expected. However, we could not find cases with bony metastases from endometrial clear cell carcinoma except for one case with paranasal sinus metastasis (26) . Because of the small number of reported cases, optimal treatment methods have not yet been established in patients with bone metastases from endometrial carcinoma.…”

Section: Skeletal Carcinomatosis In Endometrial Clear Cell Carcinoma 893contrasting

confidence: 67%

Skeletal carcinomatosis in endometrial clear cell carcinoma at initial presentation: a case report

Dursun

Gültekin

Yüce

et al. 2006

Int J Gynecol Cancer

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Bone metastasis is frequently seen in different solid tissue malignancies. However, it is a very rare entity in endometrial cancers and most of the previous reports were localized to a single bone. To the best of our knowledge, this is the first report of a case with disseminated bone metastasis from endometrial clear cell carcinoma. A 69-year-old, multiparous woman presented with the complaint of postmenopausal bleeding. Diagnostic workup revealed endometrial clear cell carcinoma. After comprehensive surgical staging, the patient was found to be at FIGO stage IIIC. Three weeks after the operation, an intractable back pain developed. Direct graphics of the lumbosacral region were suspicious of metastasis, and further evaluation of the patient revealed metastasis in multiple bones including calvarium, thoracolumbal vertebrae, pelvic bones, costae, collum of the right femur, and trochanter major of the left femur. Bone metastasis in endometrial clear cell carcinoma may be seen at initial presentation and may involve multiple bones. Whole-body scanning with scintigraphic evaluation is a reasonable approach to evaluate the extension of the bone involvement. Further studies are needed to elucidate the true incidence and management of bone metastasis in endometrial clear cell carcinoma.

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Section: Skeletal Carcinomatosis In Endometrial Clear Cell Carcinoma 893contrasting

confidence: 67%

Skeletal carcinomatosis in endometrial clear cell carcinoma at initial presentation: a case report

Dursun

Gültekin

Yüce

et al. 2006

Int J Gynecol Cancer

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“…Metastases to the paranasal sinuses from gynecologic malignant tumors are extremely rare . Reported entities have included uterine leiomyosarcoma, cervical carcinoma, fallopian tube adenocarcinoma, ovarian Sertoli/Leydig cell tumor, and endometrial carcinoma (endometrioid and clear cell carcinomas) …”

Section: Primary Tumor Sitesmentioning

confidence: 99%

Metastases to nasal cavity and paranasal sinuses

et al. 2016

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The sinonasal cavities are rare locations for metastases. Metastases to these locations are usually solitary and produce similar symptoms to those of a primary sinonasal tumor. Nasal obstruction and epistaxis are the most frequent symptoms. The maxillary sinus is most frequently involved. The most common primary tumor sites to spread to this region originate in the kidney, breast, thyroid, and prostate, although any malignancy could potentially lead to a metastasis to the paranasal sinuses. The patient's prognosis is usually poor because of the fact that the sinonasal metastasis is usually associated with widespread disseminated disease. In the majority of patients, palliative therapy is the only possible treatment option. Nevertheless, whenever possible, surgical excision either alone or combined with radiotherapy may be useful for palliation of symptoms and, rarely, to achieve prolonged survival. This review considers the most interesting cases reported in the literature that presents metastases to the sinonasal cavities. © 2016 Wiley Periodicals, Inc. Head Neck 38: 1847-1854, 2016.

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“…Maxymiw et al 33 No No RT 5 Died Nishida et al 34 No NA NA NA NA Schols et al 35 No No RT, HT (MPA) 24 NED Clarke et al 36 Lung Yes Surgery, RT 36 Died Armentano et al 19 No No Refused therapy 1 Died Scott et al 37 No No RT, CT NA NA Racha et al 38 Lung, kidney Yes Surgery 9 Died Mustafa et al 23 Lung, pelvic side wall 40 Axillar lymph nodes No RT 6 AWD Ali et al 41 Lung Yes Amputation, HT (MPA) 16 AWD Ilvan et al 42 Lung, liver, kidney No Untreated ≠ 1 D i e d Amiot at al. 43 Lung Yes Amputation NA Died Haraguchi et al 44 No Yes Surgery 60 NED Landoni et al 11 Vagina No RT NA NA Osanai et al 45 No No CT, Bisphosphonate (pamidronate)…”

Section: Nedmentioning

confidence: 99%