Enema-induced Hypocalcemia and Hyperphosphatemia Leading to Cardiac Arrest during Induction of Anesthesia in an Outpatient Surgery Center

Reedy, John; Zwiren, Gerald T.

doi:10.1097/00000542-198312000-00020

Cited by 28 publications

(13 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The remaining four clinical trials evaluated water and electrolyte disturbances after enema administration 28–31 . Of the remaining 43 references, we found conclusive data in 39 references, all of them case reports and letters to the editor 32–70 . We also found four references to enema‐induced anorectal injuries 71–74 .…”

Section: Resultsmentioning

confidence: 93%

See 1 more Smart Citation

Systematic review: the adverse effects of sodium phosphate enema

Mendoza

Legido

Rubio

et al. 2007

Aliment Pharmacol Ther

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 93%

“…Out of these 39 references, 32–70 the occurrence of side effects after administration of sodium phosphate enemas was reported in 44 patients. Twenty‐two of these patients (50%) were women and 22 men (50%).…”

Section: Resultsmentioning

confidence: 99%

Systematic review: the adverse effects of sodium phosphate enema

Mendoza

Legido

Rubio

et al. 2007

Aliment Pharmacol Ther

View full text Add to dashboard Cite

show abstract

“…The hyperosmolarity of these solutions draws fluid into the intestinal lumen to stimulate peristalsis. A number of cases of significant toxicity secondary to use of these solutions have been reported [1,2,3,4,5,6,7,8,9,10,11,12,13,15,16,17,18,19,20,21,22,23,24,25,29,30,31,32,33,34,35,36,37].…”

Section: Discussionmentioning

confidence: 99%

Respiratory failure requiring extracorporeal membrane oxygenation after sodium phosphate enema intoxication

2003

View full text Add to dashboard Cite

show abstract

“…Davies et al (1977) reported hypocalcaemia, hyperphosphataemia and dehydration after a single hypertonic phosphate enema in 2 acutely constipated infants. Reedy and Zwiren (1983) reported a case of phosphate enema-induced hypocalcaemia and hyperphosphataemia said to have caused cardiac arrest during induction of anaesthesia in a 17-month-old boy. Hirschsprung's disease had not been excluded.…”

Section: Osmotic Laxativesmentioning

confidence: 99%

Adverse Effects of Drugs Used in the Management of Constipation and Diarrhoea

1994

View full text Add to dashboard Cite

Most laxatives, if used intermittently in the absence of contraindications, are relatively safe. Bulking agents may diminish absorption of some minerals and drugs, but this is not usually clinically significant. Ispaghula can cause serious allergic reactions. The chronic ingestion of stimulant laxatives has been blamed for the development of the 'cathartic colon', but there are no definitive studies which have demonstrated this. Dantron (danthron) preparations should only be used in older patients and the terminally ill because of the risk of hepatotoxicity with this drug. Oral oxyphenisatine should no longer be used. Senna would appear to be the stimulant laxative of choice during pregnancy and lactation. Bisacodyl is the polyphenolic derivative of choice. Lactulose, sorbitol and lactilol rarely cause significant adverse effects. Magnesium salt laxatives and phosphate enemas can cause serious metabolic disturbances in babies and young children. Liquid paraffin is contraindicated if there is any risk of aspiration. Interference with the absorption of fat soluble vitamins would not appear to be clinically significant. Docusate sodium may potentiate the hepatotoxicity of other drugs, but reports of this are rare. The role of cisapride in constipation has not been established. Antidiarrhoeal drugs are second line drugs whose use is aimed at minimising inconvenience and discomfort. No antidiarrhoeals can be recommended for children under 4 years of age. Loperamide is the drug of choice in older children and adults. The atropine component of diphenoxylate/atropine combinations can cause significant adverse effects. Bismuth salicylate is an inconvenient treatment for travellers' diarrhoea as large frequent doses of the liquid formulation are needed. Some bismuth can be absorbed and there is the potential to cause encephalopathy. Octreotide, methysergide and cholestyramine have a role for specific causes of diarrhoea only. Octreotide is effective in high output states from the small or large bowel, with few adverse effects. Clonidine and lidamidine may have a role in the treatment of chronic diabetic diarrhoea. The role of lidamidine in nondiabetic chronic diarrhoea has not been established.

show abstract

Enema-induced Hypocalcemia and Hyperphosphatemia Leading to Cardiac Arrest during Induction of Anesthesia in an Outpatient Surgery Center

Cited by 28 publications

References 0 publications

Systematic review: the adverse effects of sodium phosphate enema

Systematic review: the adverse effects of sodium phosphate enema

Respiratory failure requiring extracorporeal membrane oxygenation after sodium phosphate enema intoxication

Adverse Effects of Drugs Used in the Management of Constipation and Diarrhoea

Contact Info

Product

Resources

About