Enzymes for industrial applications

Robic, Audrey; Ullmann, Christophe; Auffray, Pascal; Persillon, Cécile; Martin, Juliette

doi:10.1051/ocl/2017027

Cited by 7 publications

(3 citation statements)

References 18 publications

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“…This subject was completed by using webservers PeptideCutter (available at https://web.expasy.org/peptide_cutter/) and BIOPEP analysis ENZTME(S) ACTION (available at http://www.uwm.edu.pl/biochemia/index.php/en/biopep) 28 . Di- and tripeptides were chosen to have specific properties elimination for they can be absorbed directly into the blood circulatory system from the digestive tract 29 . Nineteen enzymes, i .…”

Section: Methodsmentioning

confidence: 99%

Novel ACE inhibitory tripeptides from ovotransferrin using bioinformatics and peptidomics approaches

Chen

Zhao

et al. 2019

Sci Rep

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Food-derived ACE inhibitory peptides have recently attracted increased attention. This work focused on a more efficient in silico method to find ACE inhibitory peptides from ovotransferrin. In this work, ovotransferrin was digested into peptides by virtual enzymolysis. Subsequently, in vitro ACE inhibitory activity of potential tripeptides was conducted following the peptide score, toxicity, and water solubility prediction. Both pharmacophore study and flexible docking were applied to analyze ACE inhibition mechanism of tripeptides. Our results demonstrated that EWL was a potent ACE inhibitory tripeptide with IC50 value of 380 ± 10 μM. Besides, pharmacophore and flexible docking showed that the pi interaction and hydrogen bond were the key interactions in ACE-EWL complex. It appears that the in vitro ACE inhibitory activity of tripeptide EWL was consistent with its molecular modeling.

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Section: Methodsmentioning

confidence: 99%

Novel ACE inhibitory tripeptides from ovotransferrin using bioinformatics and peptidomics approaches

Chen

Zhao

et al. 2019

Sci Rep

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“…As lipases (triacilglicerol acil-hidrolases, EC 3.1.1.3) têm sido utilizadas em uma ampla variedade de aplicações nas áreas de farmácia, química fina, alimentos, cosméticos, meio ambiente e energia (Robic et al, 2017). Elas pertencem à classe das serina hidrolases e catalisam a hidrólise de triacilgliceróis em glicerol, diacilgliceróis, monogliceróis e ácidos graxos livres.…”

Section: Lipaseunclassified

Microrganismos marinhos: um reservatório de hidrolases biotecnologicamente interessantes

Lopes,

Canellas,

Oliveira

et al. 2023

Rev. Biol.

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Esta revisão tem por objetivo fornecer uma revisão narrativa atualizada acerca de enzimas hidrolíticas (agarases, amilases, celulases, esterases, lipases, peptidases e quitinases) isoladas do microbioma marinho. Esses biocatalisadores apresentam propriedades bioquímicas únicas, como halotolerância, extremos de pH, temperatura e barofilicidade, que os tornam atraentes para uso em diversos setores industriais, estimulando futuras aplicações biotecnológicas. Considerando o vasto repertório enzimático dos diversos membros das comunidades microbianas vivendo no ambiente marinho, salienta-se a imprescindibilidade de acessar esse habitat, mais especificamente essas unidades biocatalíticas. Com a devida atenção voltada ao viés industrial, novos biocatalisadores serão descobertos com sucesso nas comunidades microbianas marinhas, desde a confirmação de sua atividade até a comprovação de seu emprego prático nos setores de interesse e geração de propriedade intelectual.

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“…Numerous enzyme classes with potential industrial applications have been identified ( Honda, 2017 ; Basso and Serban, 2019 ). The majority of these classes are already used in a few very specific industrial applications ( Robic et al, 2017 ). In particular, hydrolases, peptidases, lipases, cellulases, and amylases are highly used ( Shahani, 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Novel Enzymes From the Red Sea Brine Pools: Current State and Potential

et al. 2021

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The Red Sea is a marine environment with unique chemical characteristics and physical topographies. Among the various habitats offered by the Red Sea, the deep-sea brine pools are the most extreme in terms of salinity, temperature and metal contents. Nonetheless, the brine pools host rich polyextremophilic bacterial and archaeal communities. These microbial communities are promising sources for various classes of enzymes adapted to harsh environments – extremozymes. Extremozymes are emerging as novel biocatalysts for biotechnological applications due to their ability to perform catalytic reactions under harsh biophysical conditions, such as those used in many industrial processes. In this review, we provide an overview of the extremozymes from different Red Sea brine pools and discuss the overall biotechnological potential of the Red Sea proteome.

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Enzymes for industrial applications

Cited by 7 publications

References 18 publications

Novel ACE inhibitory tripeptides from ovotransferrin using bioinformatics and peptidomics approaches

Novel ACE inhibitory tripeptides from ovotransferrin using bioinformatics and peptidomics approaches

Microrganismos marinhos: um reservatório de hidrolases biotecnologicamente interessantes

Novel Enzymes From the Red Sea Brine Pools: Current State and Potential

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