2019
DOI: 10.1111/trf.15095
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Epidemic potential of Zika virus in Australia: implications for blood transfusion safety

Abstract: BACKGROUND: Zika virus (ZIKV) is transfusiontransmissible. In Australia the primary vector, Aedes aegypti, is established in the north-east, such that local transmission is possible following importation of an index case, which has the potential to impact on blood transfusion safety and public health. We estimated the basic reproduction number (R 0 ) to model the epidemic potential of ZIKV in Australian locations, compared this with the ecologically similar dengue viruses (DENV), and examined possible implicat… Show more

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Cited by 7 publications
(13 citation statements)
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“…In our previous study, we found that blood donations were predominantly distributed around the large urban centres of Sydney and Melbourne, which did not have epidemic potential for ZIKV by either mosquito species [42]. Local transmission of ZIKV in Cairns, Rockhampton or Townsville presented the highest risk to the blood supply, although these combined locations represent only 4.5% of the annual mean number of blood donations in aegypti, Cairns, and Rockhampton are the most at risk of having infected blood components obtained from individual donations with the 'worst-'case scenario (noting that Rockhampton is the only region without predominantly Wolbachia-infected strains of Ae.…”
Section: Plos Neglected Tropical Diseasesmentioning
confidence: 91%
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“…In our previous study, we found that blood donations were predominantly distributed around the large urban centres of Sydney and Melbourne, which did not have epidemic potential for ZIKV by either mosquito species [42]. Local transmission of ZIKV in Cairns, Rockhampton or Townsville presented the highest risk to the blood supply, although these combined locations represent only 4.5% of the annual mean number of blood donations in aegypti, Cairns, and Rockhampton are the most at risk of having infected blood components obtained from individual donations with the 'worst-'case scenario (noting that Rockhampton is the only region without predominantly Wolbachia-infected strains of Ae.…”
Section: Plos Neglected Tropical Diseasesmentioning
confidence: 91%
“…aegypti are wild-type (not infected with Wolbachia); iii) the human population undergoes linear growth throughout study period and ignores births and deaths; iv) vector control is present and consistent between UCLs; v) only symptomatic infections are considered infectious; vi) the protective effect of herd immunity is not considered. All parameter descriptions are summarized in S1 Table (S1 Table), with rationale for each explained in Watson-Brown et al [42].…”
Section: Estimation Of the Basic Reproduction Numbermentioning
confidence: 99%
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