Epidemiologic and genetic characteristics of mumps viruses isolated in China from 1995 to 2010

Cui, Ai‐Li; Zhu, Zhendong; Chen, Meng; Zheng, Huanying; Liu, Leng; Wang, Yan; Ma, Yanhui; Wang, Changyin; Fang, Xueqiang; Li, Ping; Guan, Ronghui; Wang, Shuang; Zhou, Jian; Zheng, Lei; Gao, Hui; Ding, Zhuang; Li, Liqun; Fang, Bo; Sun, Zhaodan; Zhang, Zhenying; Feng, Daxing; He, Jun; Hui, Chen; Jin, Li; Rota, Paul A.; Xu, Wenbo

doi:10.1016/j.meegid.2013.12.005

Cited by 35 publications

(46 citation statements)

References 16 publications

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“…The isolation of MuV was performed using the Vero/hSLAM cell line [36], which was obtained from the US CDC (Global Specialized Laboratory for measles and rubella), and the cells were harvested when the visible cytopathic effect (CPE) covered at least 75–90% of the cell layer [37]. Virus isolation was conducted by provincial laboratories, and the isolates were transported to the National Measles Laboratory (NML) in Beijing for genotyping.…”

Section: Methodsmentioning

confidence: 99%

“…RT-PCR was performed using a one-step RNA PCR kit (AMV) (TaKaRa, Japan) to amplify a 500-nt product containing the 316-nt WHO-recommended sequence window, as described previously [37]. The primers of SH5-1 () and SH5-2 () were used in the RT-PCR assay.…”

Section: Methodsmentioning

confidence: 99%

“…MuV has been shown to have 12 genotypes (A-N, excluding E and M) circulating in the world [3], among which there is large diversity. In mainland China, genotype has been the predominant MuV genotype, and it was also the native prevailing MuV genotype during 1995–2010 in mainland China [4]. …”

Section: Introductionmentioning

confidence: 99%

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Mumps Epidemiology and Mumps Virus Genotypes Circulating in Mainland China during 2013-2015

Cui

Zhu

et al. 2017

PLoS ONE

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With the implementation of mumps virus (MuV) vaccination in the expanded program on immunization (EPI) in mainland China since 2008, the incidence of mumps has decreased, and the natural epidemic pattern of mumps has slightly changed during 2013–2015. The two epidemic peaks (April-July and November-December) became less obvious than those observed from 2004 to 2012. Children and adolescents younger than 15, particularly in the five-to-nine-year-old age group, remain the target group and should be the focus of high-quality immunization activities in mainland China. However, it was also found that the incidence and reported cases of mumps decreased in each age group during 2013–2015, particularly in the five-to-nine-year-old and ten-to-fourteen-year-old age groups. The proportion of mumps cases among adults in some provinces also increased. Unlike the changes in the epidemiological characteristics of mumps affected by vaccination, the data of MuV virology surveillance indicated that most of the MuV transmission chains have not yet been effectively interrupted, and MuV remains a natural epidemic pattern in mainland China. In the MuV virology surveillance, 194 MuV strains during 2013–2015 were isolated from 10 of 31 provinces in mainland China. Based on the phylogenetic analysis of the small hydrophobic (SH) gene, both genotype (99.0%) and (1.0%) were identified, and genotype was still the predominant genotype continuously circulating in mainland China. Representative genotype and strains isolated in China from 1995 to 2012 were selected for further analysis. The results indicated that there were multiple transmission chains within genotype , with no obvious geographical or time differences. The high genetic diversity of genotype F strains could be a result of the continuous transmission and evolution of the MuV in mainland China. Genotype was also detected in four provinces in mainland China. Because of the limited epidemiological data, it was uncertain whether the genotype MuV strains found in 2011 and 2013 were imported from other countries. Therefore, combined high-quality epidemiological and virological surveillance is necessary for mumps control; it can also be used to observe the changes in epidemiological characteristics and viral transmission of mumps over time after mumps-containing vaccine (MuCV) implementation and to provide a comprehensive epidemiological and genetic baseline for mumps elimination in mainland China.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Mumps Epidemiology and Mumps Virus Genotypes Circulating in Mainland China during 2013-2015

Cui

Zhu

et al. 2017

PLoS ONE

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“…For example, a distinct seasonal variation was detected in the USA, with a peak occurring in April. 9 Other countries such as Ireland, 10 China, 11,12 and Jordan 13 a peak in autumn, early-summer, winter and spring, respectively was also reported. Although these phenomena have not been well explained, the seasonality of mumps provides evidence that meteorological factors might play a key role in its occurrence.…”

Section: Introductionmentioning

confidence: 95%

The association between the incidence of mumps and meteorological parameters in Taiwan

et al. 2015

Human Vaccines & Immunotherapeutics

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These authors equally contributed to this work. Keywords: infectious disease, meteorological parameters, modeling, mumps, weatherMumps is caused by a paramyxovirus. It is an acute, but mild infectious disease. However, approximately 10% of patients with mumps can develop severe meningoencephalitis, disability, and death. Seasonal patterns in mumps vary across countries, but the reasons for this phenomenon remain unclear. The aim of this study was to assess the role of meteorological factors on mumps infection. We investigated the relationships between weather variability and the incidence of mumps in Taiwan using a Poisson regression analysis and case-crossover methodology. Between 2006 and 2011, 6,612 cases of mumps were reported to the Centers for Disease Control, Taiwan (Taiwan CDC). The incidence of mumps showed a significant seasonality in summertime (for oscillation, P < 0.001). The number of mumps started to increase at temperatures of 20 C (r 2 D 0.73, P < 0.001), and the case count of mumps began to decline when the temperatures were higher than approximately 25 C (r 2 D 0.24, p D 0.04), producing an inverted V-shaped relationship. Similarly, the number of mumps began to increase at a vapor pressure of 5-9 hPa (r 2 D 0.87, P < 0.005) and decreased at a vapor pressure higher than 25-29 hPa (r 2 D 0.21, p D 0.05). The number of mumps cases was positively associated with temperature and vapor pressure in the preceding period of the infection. In conclusion, this study showed that the occurrence of mumps is significantly associated with increasing temperature and vapor pressure in Taiwan. Therefore, these factors could be regarded as warning signals indicating the need to implement preventive measures.

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“…The SH gene sequence of this strain was compared with that of MuV stains in the GenBank database, and the nucleotide identity score was highest (94z) among the strains detected in various parts of China since 2000 (8). However, the origin of the MuVi/Kobe.JPN/980168.98 strain is unknown from the GenBank database.…”

mentioning

confidence: 99%

Genotyping of Mumps Virus Strains Detected in Kobe City from 1991 to 2012

Akiyoshi¹,

Suga

2014

Jpn J Infect Dis

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Epidemiologic and genetic characteristics of mumps viruses isolated in China from 1995 to 2010

Cited by 35 publications

References 16 publications

Mumps Epidemiology and Mumps Virus Genotypes Circulating in Mainland China during 2013-2015

Mumps Epidemiology and Mumps Virus Genotypes Circulating in Mainland China during 2013-2015

The association between the incidence of mumps and meteorological parameters in Taiwan

Genotyping of Mumps Virus Strains Detected in Kobe City from 1991 to 2012

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