Epidemiology and pathogenesis of   infections

Kotiranta, Anja; Lounatmaa, Kari; Haapasalo, Markus

doi:10.1016/s1286-4579(00)00269-0

Cited by 558 publications

(405 citation statements)

References 79 publications

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“…Members of the B. cereus group are ubiquitously present in the environment and can adapt to a wide range of environmental conditions (Abee & Wouters, 1999;Jensen et al, 2003;Kotiranta et al, 2000). This raises the question of how these organisms are able to monitor these conditions and respond to them.…”

Section: Introductionmentioning

confidence: 99%

Comparative analysis of two-component signal transduction systems of Bacillus cereus, Bacillus thuringiensis and Bacillus anthracis

et al. 2006

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Members of the Bacillus cereus group are ubiquitously present in the environment and can adapt to a wide range of environmental fluctuations. In bacteria, these adaptive responses are generally mediated by two-component signal transduction systems (TCSs), which consist of a histidine kinase (HK) and its cognate response regulator (RR). With the use of in silico techniques, a complete set of HKs and RRs was recovered from eight completely sequenced B. cereus group genomes. By applying a bidirectional best-hits method combined with gene neighbourhood analysis, a footprint of these proteins was made. Around 40 HK-RR gene pairs were detected in each member of the B. cereus group. In addition, each member contained many HK and RR genes not encoded in pairs (‘orphans’). Classification of HKs and RRs based on their enzymic domains together with the analysis of two neighbour-joining trees of these domains revealed putative interaction partners for most of the ‘orphans’. Putative biological functions, including involvement in virulence and host–microbe interactions, were predicted for the B. cereus group HKs and RRs by comparing them with those of B. subtilis and other micro-organisms. Remarkably, B. anthracis appeared to lack specific HKs and RRs and was found to contain many truncated, putatively non-functional, HK and RR genes. It is hypothesized that specialization of B. anthracis as a pathogen could have reduced the range of environmental stimuli to which it is exposed. This may have rendered some of its TCSs obsolete, ultimately resulting in the deletion of some HK and RR genes.

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Section: Introductionmentioning

confidence: 99%

Comparative analysis of two-component signal transduction systems of Bacillus cereus, Bacillus thuringiensis and Bacillus anthracis

et al. 2006

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“…In Japan, the emetic type is reported about 10 times more frequently than the diarrhoeal type; while in Europe and North America, the diarrhoeal type is the most frequently reported (KOTIRANTA; LOUNATMAA; HAAPASALO, 2000). In the Netherlands, for example, from 1991 to 1994, B. cereus was identified as the most common cause (19%) of food poisoning outbreaks (SIMONE et al, 1997).…”

Section: Discussionmentioning

confidence: 99%

Detection of enterotoxins produced by B. cereus through PCR analysis of ground and roasted coffee samples in Rio de Janeiro, Brazil

Souza¹,

Abrantes²

2011

Ciênc. Tecnol. Aliment.

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“…It is able to form spores and very resistant to low and high temperatures 15 . Staphylococcus aureus is a Gram-positive, facultative anaerobic coagulase-positive catalase-positive potential pathogen and found in skin, soft tissue, bone joint, endovascular and wound infections.…”

Section: Figure 1 General Representation Of the Structure Of A Schifmentioning

confidence: 99%

Design, Synthesis and Biological Evaluation of Some Schiff Base Ligand as Antimalarial Agents.

Garg¹,

Acharya

Patel³

2013

Int Jour of Biomed Res

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Epidemiology and pathogenesis of infections

Cited by 558 publications

References 79 publications

Comparative analysis of two-component signal transduction systems of Bacillus cereus, Bacillus thuringiensis and Bacillus anthracis

Comparative analysis of two-component signal transduction systems of Bacillus cereus, Bacillus thuringiensis and Bacillus anthracis

Detection of enterotoxins produced by B. cereus through PCR analysis of ground and roasted coffee samples in Rio de Janeiro, Brazil

Design, Synthesis and Biological Evaluation of Some Schiff Base Ligand as Antimalarial Agents.

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