1959
DOI: 10.1902/jop.1959.30.4.298
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Epidemiology of Diabetes Mellitus: II. A Study of 100 Dental Patients

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Cited by 42 publications
(19 citation statements)
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“…Although the mechanisms by which diabetes and smoking increase the severity of periodontal disease are poorly understood, one may propose that increased susceptibility to periodontal infection, impaired host response and excessive collagenolytic activity all play a major role. 32 Sheridan et al 33 showed that pocket formation, presence of calculus, increased tooth mobility and tooth loss occurred with greater frequency in patients with a decreased glucose tolerance. A positive association between the variations in blood glucose level and the degree of periodontal disease was reported in DM 34 and our results agree with these findings.…”
Section: Discussionmentioning
confidence: 99%
“…Although the mechanisms by which diabetes and smoking increase the severity of periodontal disease are poorly understood, one may propose that increased susceptibility to periodontal infection, impaired host response and excessive collagenolytic activity all play a major role. 32 Sheridan et al 33 showed that pocket formation, presence of calculus, increased tooth mobility and tooth loss occurred with greater frequency in patients with a decreased glucose tolerance. A positive association between the variations in blood glucose level and the degree of periodontal disease was reported in DM 34 and our results agree with these findings.…”
Section: Discussionmentioning
confidence: 99%
“…Sheridan et al 19 showed that pocket formation, presence of calculus, increased tooth mobility and tooth loss occurred with gr e ater frequency in p atients with a decreased glucose tolerance. Albrecht et al 17 have shown that mean DMFT values were higher amongst diabetics than amongst the controls, but attributed this difference to the M component, which they felt was increased due to the high prevalence of periodontal disease amongst diabetics.…”
Section: Discussionmentioning
confidence: 99%
“…2829 Individuals with a decreased glucose tolerance showed a higher rate of pocket formation, presence of calculus, increased tooth mobility and tooth loss. 30 Variable models have been developed to give reason to this correlation such as periodontal chronic inflammation which results in increased circulating cytokines and inflammatory mediators, autoimmune response to the chronic periodontal infection that gives way to endothelial dysfunction, or the presence of certain factors that leads to increased inclination both to periodontal disease and diabetes vascular diseases at the same time. 31 Statistically significant relation has been detected between the HbA1C levels of the patients and the biomass, haemolysin activity and proteinase activity.…”
Section: Diabetes and Periodontal Diseasementioning
confidence: 99%