Epidermoid Cyst of Intrapancreatic Accessory Spleen

Ru, Kun; Kalra, Aarti; Ucci, Angelo A.

doi:10.1007/s10620-006-9376-x

Cited by 28 publications

(6 citation statements)

References 9 publications

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“…[4] reported the first case of ECIPAS; and since then 33 articles and 36 patients have been reported in the English language literature (Table 1), suggesting the rarity of the disease. However, the exact incidence of ECIPAS is difficult to determine as over 50% of the cases were incidentally detected [8,9,12,14,15,18,19,22-24], [26,27,30,32,34]. The mean age of the patients was 46.1 years (range 12 to 70 years), with a female preponderance (58.3%) [6,7,10-13,16,17,19-21,24-26,28], [31,33,34,36].…”

Section: Discussionmentioning

confidence: 99%

“…No skin appendages have been identified [4-34]. Immunohistochemical examinations of lining epithelium demonstrate positivity for CA 19-9 [6,10-12,15,18,20,22,24,27], [30] and CEA [10-12,15,22,24,29]. Our immunohistochemical findings were found to accord with those of the above mentioned studies, showing positivity for anti-CA 19-9 and anti-pCEA antibodies.…”

Section: Discussionmentioning

confidence: 99%

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Epidermoid cyst of an intrapancreatic accessory spleen: a case report and literature review

et al. 2014

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BackgroundAn epidermoid cyst in an intrapancreatic accessory spleen is a rare lesion. Despite advances in radiologic techniques, in most cases it has been diagnosed preoperatively as a possible pancreatic neoplasm.Case presentationHerein, we present a 63-year-old Caucasian woman, diagnosed preoperatively with enhanced-contrast abdominal computed tomography, as having a potential cystic tumor in the tail of the pancreas. The patient underwent a distal pancreatectomy and splenectomy, and the histological examination revealed the presence of an epidermoid cyst of an accessory intrapancreatic spleen.ConclusionsFamiliarity with the imaging features, the clinical presentation and the location of the cyst are important to consider if this rare entity is to be included in the differential diagnosis of cystic neoplasms of the pancreas.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Epidermoid cyst of an intrapancreatic accessory spleen: a case report and literature review

et al. 2014

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“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] All of these patients underwent a surgical resection because they were diagnosed to have pancreatic tumors, which were possibly malignant cystic tumors. If epidermoid cysts of the accessory spleen can be diagnosed accurately, and are small and asymptomatic, surgery may not be necessary.…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic resection of an epidermoid cyst originating from an intrapancreatic accessory spleen: Report of a case

et al. 2009

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A 67-year-old man underwent an investigation of epigastric pain and weight loss. Preoperative imaging findings suggested the presence of a tumor, which developed as an epidermoid cyst and originated from an intrapancreatic accessory spleen; however, the possibility of malignancy could not be ruled out. We therefore performed a laparoscopic-assisted distal pancreatectomy with a splenectomy for both diagnostic and treatment purposes. Five laparoscopic ports were created. After the spleen and pancreatic tail were dissected from the retroperitoneum laparoscopically, they were pulled out through a 7-cm left subcostal incision and resected with an endoscopic linear stapler. The operative time was 227 min and the blood loss was 400 ml. The postoperative course was uneventful. The final pathological diagnosis was in agreement with the preoperative diagnosis. This case demonstrates that the minimally invasive approach of laparoscopic surgery can be used safely and successfully for difficult-to-diagnose pancreatic tumors. This is the first report describing a laparoscopic resection of an epidermoid cyst originating from an intrapancreatic accessory spleen.

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“…Since Davidson et al [1] reported the first case of an epidermoid cyst originating from an intrapancreatic accessory spleen in 1980, there have been 16 additional cases reported in the English literature [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. All of them have been the subject of only sporadic case reports.…”

Section: Introductionmentioning

confidence: 99%

Epidermoid Cyst in an Intrapancreatic Accessory Spleen: Three Case Reports and Review of the Literatures

Kadota

Kushida

Miyai

et al. 2009

Pathol. Oncol. Res.

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The development of an epidermoid cyst in an intrapancreatic accessory spleen is an extremely rare lesion, with only 17 cases being reported in the English literature. All such cases were located in the pancreatic tail, some of which showed carbohydrate antigen 19-9 (CA19-9) immunoreactivity in the lining of the epithelium. A few of them indicated an elevation of the serum CA19-9 level. Here we report three cases of an epidermoid cyst in an intrapancreatic accessory spleen. Cases 1 and 2 were 57-year-old and 70-year-old women, while case 3 was a 37-year-old man. All three cases were asymptomatic. Serum CA19-9 levels showed within normal limits (case 1), slightly elevated (case 2), and clearly elevated (case 3). They underwent a distal pancreatectomy with splenectomy (cases 1 and 2) and without splenectomy (case 3). Grossly, the surgical specimen was a well-demarcated, multiple (case 1) or solitary (cases 2 and 3) cystic mass in the pancreatic tail. A high level of fluid CA 19-9 was detected in case 1. Microscopically, the cystic walls were lined with squamous and cuboidal epithelium, which were surrounded by normal splenic tissue and hyalinized fibrous tissue. The lining squamous epithelium was revealed as nonkeratinizing (Cases 1 and 2) or keratinizing (Case 3). Immunohistochemically, CA19-9 was positive in the monolayer and surface layer of the cuboidal epithelium, but negative for the keratinizing squamous epithelium. As for the histogenesis, it is suggested that the cystic lining of the epithelium may derive from the pancreatic duct which protrudes into the accessory spleen.

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Epidermoid Cyst of Intrapancreatic Accessory Spleen

Cited by 28 publications

References 9 publications

Epidermoid cyst of an intrapancreatic accessory spleen: a case report and literature review

Epidermoid cyst of an intrapancreatic accessory spleen: a case report and literature review

Laparoscopic resection of an epidermoid cyst originating from an intrapancreatic accessory spleen: Report of a case

Epidermoid Cyst in an Intrapancreatic Accessory Spleen: Three Case Reports and Review of the Literatures

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