Epilepsy and Depression: A Bidirectional Relationship

Gnanavel, Sundar

doi:10.4103/jnrp.jnrp_203_17

Cited by 8 publications

(13 citation statements)

References 6 publications

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“…In our study 16.5 % mentioned there become nervous personality, but 56.3 % there have no change in personality. Study done by Gnanavel et al, showed depression is high in epileptic patients reach up to 55% [35]. Same results in our study, one case feels he is depressed all the time, 47.6 % feel sometimes depressed, and 40.8 % feel no any kind of depression, In our study 75.7 % mentioned there is a problem with memory, 55.4% of patients associated with di culty on concentrating on reading, 45.6 % can do any task with no problem, 54.4 % associated with problem to complete and concentrating on the task, in comparison with study done by Hermann and Seidenberg et al showed there is global decrease and impairment of the cognitive function in 47% of cases [36].…”

Section: Discussionmentioning

confidence: 97%

The quality of life among Sudanese Patients with Epilepsy, Khartoum, Sudan

Ibrahim

Ali²,

Ahmed

et al. 2021

Preprint

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Introduction:This is the first study done in the national center for neurological sciences, Khartoum state to assess the quality of life above hundred Sudanese epileptic patients, in the period from September to December 2020.Methodology: This is a descriptive cross sectional study, data was collected using interviewing questionnaire and this questionnaire was modified from SF-36 model.Results: Most of the patients are from the urban area (60.2%), housewives are most of them, most of the patients were single and from low socioeconomic status, the history of the disease was less than three years for most of the cases covered in this study, most type is generalized tonic clonic epilepsy, normal EEG finding in 75.7% and normal MRI brain in 78.6%, most of patients mentioned they have no attack in last month. Regarding mental health 47.6% feel sometimes depression, 75.7% associated with memory problems. Regarding physical health 51.5% feel energetic all of the time, 9.7% always associated with sleep disturbance, most of patients are not driving, neither having hobbies for leisure time. 63.1% don’t have any health problem, 32% feel stigma if attack happen in public. Commonest medication prescribed was carbamazepine and 73.8% are fully complaints with medication. 95.1% are not worried about long term medication use.Conclusion: lower level of education and manual labor associated with poor quality of life, epilepsy had bad impact on social life, there is global decrease in cognitive function, most of the patients don`t worry about side effects and duration of the medication usage

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Section: Discussionmentioning

confidence: 97%

The quality of life among Sudanese Patients with Epilepsy, Khartoum, Sudan

Ibrahim

Ali²,

Ahmed

et al. 2021

Preprint

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“…30,37 In addition to pharmacotherapy, there is increasing evidence of the benefit of psychological therapies such as cognitive behavioral therapy delivered in person or online for patients with epilepsy. 31,38 Other clinical variables such as type of epilepsy, duration of epilepsy, and type and number of antiepileptic medications were not found to be associated with major depression or dysthymia in the final regression analysis. This finding is similar to other studies [39][40][41] but different from others.…”

Section: Discussionmentioning

confidence: 87%

“…28 Depression can also cause seizures by causing sleep deprivation. 31 This makes the evaluation and treatment of depression an important part of the treatment of patients with epilepsy, as depression in people with epilepsy is often underrecognized and untreated, with an attendant negative effect on medication adherence, seizure control, and an increased risk of suicide. 17,32,33 With regard to semiology, the most common depressive symptoms reported by our sample include crying, loss of pleasure, self-dislike, loss of energy, tiredness/fatigue, indecisiveness, and punishment feelings.…”

Section: Discussionmentioning

confidence: 99%

Depression in Patients with Epilepsy in Nigeria: Phenomenology and Predictors

Ogundare

2021

International Journal of Epilepsy

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Objectives To determine the correlates of depression among patients with epilepsy in Neuropsychiatric Hospital, Aro, Abeokuta, Nigeria. Methods 270 patients with epilepsy attending the outpatient clinic of the hospital were recruited and assessed using sociodemographic questionnaire, MINI-Plus, and BDI-II. Results The mean (standard deviation [SD]) age of the respondents was 32 (9.9) years, 45.6% were females, and 38.5% were married. Thirty-two (11.9%) patients had a diagnosis of major depressive disorder (MDD) and 13 (4.8%) had a diagnosis of dysthymia. The most common depressive symptoms were loss of pleasure (84.4%), crying (84.4%), self-dislike (81.3%), and loss of energy, tiredness/fatigue, indecisiveness and punishment feelings (78.1% each). Vegetative symptoms such as changes in appetite and sleep and loss of interest in sex were the least common depressive symptoms. In the logistic regression, seizure frequency was the single predictor of MDD and dysthymia. Patients who had at least one seizure per week were five times more likely to develop MDD (OR = 5.1, p = 0.014) and 16 times likely to have dysthymia (OR= 16.0, p = 0.0007). Patients who had at least one seizure per month were 3 times more likely to develop MDD (OR = 3.3, p = 0.029). Conclusion Seizure frequency is an independent predictor of depression among patients with epilepsy. Patients with poor seizure control are at higher risk of developing depression and should be routinely screened for depression.

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Section: Discussionmentioning

confidence: 87%

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2021

International Journal of Epilepsy

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Epilepsy and Depression: A Bidirectional Relationship

Cited by 8 publications

References 6 publications

The quality of life among Sudanese Patients with Epilepsy, Khartoum, Sudan

The quality of life among Sudanese Patients with Epilepsy, Khartoum, Sudan

Depression in Patients with Epilepsy in Nigeria: Phenomenology and Predictors

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