Epithelial salivary glands neoplasms in children and adolescents: A forty‐four‐year experience

Ribeiro, Karina de Cássia Braga; Kowalski, Luiz Paulo; Saba, L.; Camargo, Beatriz de

doi:10.1002/mpo.10168

Cited by 101 publications

(126 citation statements)

References 23 publications

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“…Guzzo et al [27] reported that parotid gland is the main site for pediatric salivary gland tumors (79 %), 71 % of salivary gland tumors are benign, all benign tumors are PA, and the most common malignant tumor is MEC in the pediatric group. In studies by Ribeiro et al [28] and Liu et al [29] very high malignancy rates in pediatric groups were reported: 71 and 54 %, respectively. Shapiro and Bhattacarrya [30] reported that MEC and ACIN-CC consist 43 and 34 % of all pediatric salivary gland malignancies involving major glands.…”

Section: Pediatric Groupmentioning

confidence: 91%

Salivary Gland Tumors in Turkey: Demographic Features and Histopathological Distribution of 510 Patients

Kızıl

Aydíl

Ekinci

et al. 2012

Indian J Otolaryngol Head Neck Surg

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The aim of this study was to evaluate the demographic and clinicopathologic data of salivary gland tumors managed at a tertiary referral medical center in Turkey. The data of 510 patients with salivary gland tumors managed during the period of January 1984 to May 2012, were reviewed. Only primary neoplasms derived from salivary glands were included. Out of 510 neoplasms, 352 (69.0 %) were classified as benign and 158 (31.0 %) were classified as malignant. There was a male predominance and male:female ratio was 1.23 (281/229). The most common location was parotid gland (372/510, 72.9 %) followed by minor salivary glands (97/510, 19.0 %) and submandibular gland (40/510, 7.9 %). The malignancy rates were 21.5, 40.0, and 56.7 % in parotid, submandibular, and minor salivary glands locations, respectively. The most common location for minor salivary gland neoplasms was oral cavity (61/97, 62.9 %). Pleomorphic adenoma (PA) was the most common histopathological type (45.3 %) in the whole study group and also among pediatric patients. The most common malignant neoplasms were adenoid cystic carcinoma (39/510, 7.6 %) and mucoepidermoid carcinoma (5.7 %). Salivary gland tumors are more common in men. The malignancy rate is almost three times higher in neoplasms derived from minor glands when compared to parotid gland. PA is the most common histopathological tumor type in all locations and in all age groups.

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Section: Pediatric Groupmentioning

confidence: 91%

Salivary Gland Tumors in Turkey: Demographic Features and Histopathological Distribution of 510 Patients

Kızıl

Aydíl

Ekinci

et al. 2012

Indian J Otolaryngol Head Neck Surg

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“…However, malignant neoplasias were not verified in the first decade of life, while only two cases were diagnosed in the second decade -both of them were mucoepidermoid carcinomas. Studies carried out with children presenting salivary glandular neoplasias and at age below 19 concluded that mucoepidermoid carcinoma was also the most frequent neoplasia found in this age range 6 .…”

Section: Discussionmentioning

confidence: 95%

“…Benign tumors are the most frequent types, corresponding to 54-79% of these diseases, while malignant tumors account for 21-46% of tumors 3,5,6 .…”

Section: Introductionmentioning

confidence: 99%

Perfil epidemiológico das neoplasias de glândulas salivares: análise de 245 casos

Lima¹,

Soares²,

Amorim³

et al. 2005

Rev. Bras. Otorrinolaringol.

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Aim:The aim of the present study is to establish the relative frequency and distribution of benign and malignant epithelial neoplasms of salivary glands in the Pathology and Cytology Laboratory, Study design: Historic cohort. Material and method: in the state of Sergipe, during the period 1980-1999. The neoplasms were individualized by gender, age, race of the patients, anatomic localization of the lesions and histopathological diagnosis. Results: Out of 162,312 registered cases, 245 were salivary gland epithelial neoplasms and 187 (76.33%) were benign and 58 (23.67%) were malignant. Pleomorphic adenoma was the most frequent benign neoplasm (89.94%) and adenoid cystic carcinoma represented the most prevalent malignant neoplasm (22.41%). The benign neoplasms occurred mainly between the second and third decades of life and showed preference for female, while malignant neoplasms were diagnosed between the sixth and seventh decades of life and in women. Conclusion: The data demonstrated that epidemiology profile of the studied neoplasms corroborated most of the studied literature.

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“…The major salivary glands are affected more often, usually represented by the parotid [22][23] . Kolude 24 analyzed 34 MEC patients and found that only 25% of the lesions affected the minor salivary glands, most of which in the palate.…”

Section: Discussionmentioning

confidence: 99%

Mucoepidermoid carcinoma of the retromolar region: report of a clinical case

Gomes

Silva

Pereira

et al. 2015

RGO, Rev. Gaúch. Odontol.

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Although the number of reported cases is low, mucoepidermoid carcinoma is the most common malignant salivary gland neoplasm in RESUMOEmbora apresente uma casuística baixa, o Carcinoma Mucoepidermoide é a neoplasia maligna de glândula salivar mais observada na cavidade oral. Possui etiopatogenia desconhecida e, clinicamente, apresenta-se como tumefação sintomática ou não, sendo o palato, o sítio de predileção. Em decorrência da sua grande diversidade biológica, o tratamento e prognóstico dependem do grau histológico, da localização e do estágio clínico do tumor. O presente trabalho teve por objetivo descrever um caso clínico de carcinoma mucoepidermoide de uma paciente do gênero feminino, 45 anos de idade, feoderma. O exame físico intraoral evidenciou, em região retromolar esquerda, bolha de limites nítidos, medindo cerca de 1,0 cm de diâmetro, coloração azulada, presente há aproximadamente quatro meses. Diante do diagnóstico clínico de mucocele, foi realizada a biopsia excisional; durante a execução da mesma, observou-se extravasamento de muco amarelado. Após o resultado anatomopatológico de carcinoma mucoepiderrmoide, a paciente foi encaminhada ao cirurgião de cabeça e pescoço. Desta forma, enfatiza-se a importância do diagnóstico precoce e correto manejo desta patologia, que, mesmo quando sua aparência clínica não sugerir malignidade, deve ser considerada como hipótese diagnóstica em lesões proliferativas da boca.Termos de indexação: Diagnóstico. Glândulas salivares menores. Carcinoma mucoepidermoide.

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Epithelial salivary glands neoplasms in children and adolescents: A forty‐four‐year experience

Abstract: Epithelial salivary gland tumors are very rare in children. Surgery is the best option to achieve high cure rates and radiotherapy must have precise indications because of their long-term side effects in young age.

Cited by 101 publications

References 23 publications

Salivary Gland Tumors in Turkey: Demographic Features and Histopathological Distribution of 510 Patients

Salivary Gland Tumors in Turkey: Demographic Features and Histopathological Distribution of 510 Patients

Perfil epidemiológico das neoplasias de glândulas salivares: análise de 245 casos

Mucoepidermoid carcinoma of the retromolar region: report of a clinical case

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