Epithelioid cell granuloma in the bone marrow secondary to Epstein-Barr virus infection

Presence and persistence of hepatitis E virus RNA and proteins in human bone marrow

“…Bone marrow is one of the most important organs of human. Many pathogens, including Leishmania [3], Epstein-Barr virus (EBV) [4], parvovirus [5] and human pegivirus [6], can be detected in bone marrow and sometimes causing relevant haematologic diseases. To date, direct detection of HEV in human bone marrow has never been documented.…”

Epithelioid granulomas with proliferating T‐lymphocytes in bone marrow in a patient with infectious mononucleosis modified by secondary hemophagocytic lymphohistiocytosis

“…In infectious mononucleosis, which is caused by primary infection with Epstein-Barr virus (EBV), an occurrence of granulomas has not been well documented, especially in bone marrow (Supporting Information S3: References 3-5). 1 Here we report a case of infectious mononucleosis with secondary hemophagocytic lymphohistiocytosis (HLH), in which epithelioid granulomas were found in the bone marrow. We analyzed reactions of T-lymphocytes in the bone marrow, to reveal the presence of proliferative activity.…”