Esmolol — just another beta blocker?

Hall, Richard

doi:10.1007/bf03008284

Cited by 8 publications

(3 citation statements)

References 69 publications

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“…When the effect of stimulus wear off, as occurs at 10 min postintubation, the drug's effect takes over and pulse rates go below baseline values. My study corroborates with the findings of Suman Shree et al 2003 [13] . Esmolol (I) was completely ineffective as there was no significant difference between it and labetalol (II) during the study period (p > 0.05).…”

Section: Discussionsupporting

confidence: 92%

Attenuation of cardiovascular response during laryngoscopy and intubation: A comparative study of I.V Esmolol and labetalol

Patro¹,

K²

2019

Int. J. Med. Anesthesiology

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Introduction: Laryngoscopy and endotracheal intubation causes reflex responses in the cardiovascular system which leads to changes in the blood pressure, heart rate and sometimes arrhythmia. These responses are of short duration and may be of little consequence in young healthy patients but can be detrimental to patients with hypertension, coronary artery disease, raised intracranial pressure, cerebral aneurysm and bronchial asthma. Materials and Methods: A prospective study conducted at Department of Anaesthesiology in a Tertiary care teaching hospital from March 2019 to October 2019. 80 patients of age group 18-60 years belonging to ASA Grade I and II of either sex posted for elective surgeries of various surgical units requiring endotracheal intubation under general anaesthesia were considered for study in a randomised single blinded manner. They were divided into 2 groups consisting of 40 patients each. Group I(E): Received I.V Esmolol Hydrochloride 0.5mg/kg diluted to 10 ml with normal saline. Group II(L): Received i.v Labetalol Hydrochloride 0.25mg/kg diluted to 10 ml with normal saline.

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Section: Discussionsupporting

confidence: 92%

Attenuation of cardiovascular response during laryngoscopy and intubation: A comparative study of I.V Esmolol and labetalol

Patro¹,

K²

2019

Int. J. Med. Anesthesiology

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“…Others have found a combination of esmolol and fentanyl [8,19] or alfentanil [20] were better than either agent alone. The combination of esmolol with an opioid, or the use of higher doses of esmolol, does however carry the risk of hypotension [21], though the rapid metabolism of esmolol should ensure that this is transient.…”

Section: Discussionmentioning

confidence: 99%

A comparison of the nasal mask and the nasopharygeal airway in paediatric chair dental anaesthesia

1997

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SummaryThis study compared the quality of anaesthesia and surgical access afforded by two techniques for the administration of anaesthesia during paediatric chair dental procedures. A total of 50 ASA 1 paediatric day case patients were randomly assigned to receive anaesthesia through either the traditional Goldman nasal mask or through a nasopharyngeal airway. Patients in the nasal mask group were judged to have significantly worse airway patency (p = 0.0001) and significantly more episodes of airway obstruction (14 vs. 4; p = 0.0032) than those in the nasopharygeal airway group. Anaesthetic, surgical and oxygen saturation data did not differ significantly between the two groups. Operating conditions were universally graded as excellent in the nasopharyngeal airway group, while those in the nasal mask group were graded as excellent/good in only 79% of cases (p < 0.0001). These results suggest that better quality anaesthesia and operating conditions can be achieved by using a nasopharyngeal airway rather than the traditional nasal mask for the administration of anaesthesia to paediatric chair dental patients.Keywords Anaesthesia; dental. Equipment; nasopharyngeal airway, tracheal tube, nasal mask.. ..................................................................................... Correspondence to: Dr O. Bagshaw Accepted: 3 February 1997 Paediatric chair dental surgery is a challenge to both the anaesthetist and the surgeon. The children are outpatients, not previously assessed by an anaesthetist, unpremedicated and often frightened and uncooperative. The anaesthetist and the surgeon have to share the airway and the problems of airway obstruction, oxygen desaturation and poor surgical access are common [1, 2].The technique of using a nasopharyngeal airway for both the maintainance of airway patency and the administration of general anaesthesia is historically well described [3][4][5], but there have been no recent reports of its usefulness as an alternative to the nasal mask. Traditionally, the nasopharyngeal airway has been made from rubber and was of a fixed length, which varied depending on the size of the airway selected. Recently, we have been using this technique substituting disposable tracheal tubes for the rubber airway. These have the advantages of being single-use, the length can be readily altered and they can be easily connected to a standard anaesthetic breathing system. The aim of this study was to compare the quality of anaesthesia and surgical access afforded by these two techniques and to note any associated morbidity. MethodsLocal Ethics Committee approval for the study was obtained. The majority of children presenting for daycase chair dental surgery were eligible for inclusion in the study. Children requiring tracheal intubation for conservation work were not studied. Informed consent was obtained from a parent.A total of 50 ASA 1 children were randomly assigned to either the Nasal Mask group or the Nasopharyngeal 786ᮊ 1997 Blackwell Science Ltd Airway group. All patients were unprem...

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“…When translating these results into clinical practice, anesthesiologists have naturally used esmolol for its fast onset, short half-life, and effectiveness for these purposes. [5][6][7][8][9] Boezaart et al 10 first studied the i.v. effects of esmolol on the endoscopic SF.…”

mentioning

confidence: 99%

Intravenous Esmolol Infusion Improves Surgical Fields during Sevoflurane-Anesthetized Endoscopic Sinus Surgery: A Double-Blind, Randomized, Placebo-Controlled Trial

Shen

Weitzel

Lai

et al. 2011

Am J Rhinol�Allergy

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Esmolol — just another beta blocker?

Cited by 8 publications

References 69 publications

Attenuation of cardiovascular response during laryngoscopy and intubation: A comparative study of I.V Esmolol and labetalol

Attenuation of cardiovascular response during laryngoscopy and intubation: A comparative study of I.V Esmolol and labetalol

A comparison of the nasal mask and the nasopharygeal airway in paediatric chair dental anaesthesia

Intravenous Esmolol Infusion Improves Surgical Fields during Sevoflurane-Anesthetized Endoscopic Sinus Surgery: A Double-Blind, Randomized, Placebo-Controlled Trial

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