Essential oil ofNepetagenus (Lamiaceae) from Iran: a review

Asgarpanah, Jinous; Sarabian, Sanaz; Ziarati, Parisa

doi:10.1080/10412905.2013.851040

Cited by 38 publications

(30 citation statements)

References 42 publications

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“…Essential oil composition of the Nepeta species has been varying according to the growing region, environmental conditions and soil type, which they are generally divided into two groups nepetalactone containing and nepetalactoneless as reported in (Asgarpanah et al, 2014;Formisano et al, 2013;Sharma and Cannoo 2013;Başer, 2000;Skaltza et al, 2000). In accordance with our results, sesquiterpenes were the major compounds (73%) of N. cilicica oil.…”

Section: Discussionmentioning

confidence: 99%

“…The chemical composition of the essential oils derived from Nepeta can be of two categories. Nepetalactone containing and nepetalactoneless group that are generally rich in 1,8-cineole (most abundant), pinenes, -caryophyllene, -farnesene, caryophyllene oxide, -citral and -citronellol (Asgarpanah et al, 2014;Sharma and Cannoo, 2013;Skaltza et al, 2000). Nepetalactone isomers 4a ,7 ,7a -nepetalactone, 4a ,7 ,7a -nepetalactone, 4a ,7 ,7a -nepetalactone, 4a ,7 ,7a -nepetalactoneand 4a ,7 ,7a -nepetalactone are considered as biochemical indicator of the nepetalactone-rich group of Nepeta essential oils.…”

Section: Introductionmentioning

confidence: 99%

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Chemical composition and biological activity of Nepeta cilicica

İşcan

Göğer

Demirci

et al. 2017

Bangladesh J Pharmacol

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In the present study, aerial parts of Nepeta cilicica were hydro-distilled for the essential oil. Furthermore, air-dried plant materials were extracted with methanol. According to GC-MS results, 35 compounds were characterized in the oil (totally 92%). Caryophyllene oxide, β-caryophyllene and spathulenol (28.2, 8.9 and 4.2%) were found as main components of the oil. Sixteen compounds were detected by LC/MS, most of which were caffeoylquinic acid, luteolin and apigenin derivatives, in methanolic extract of the N. cilicica. Apart from DPPH radical scavenging activity, inhibitory effects on bacterial and yeast growth of essential oil and the methanolic extract were evaluated. Twenty-four different pathogenic bacterial and Candida strains were tested by M7-A7 and CLSI M27-A2 protocols respectively. The crude extract showed better inhibitory effects against bacteria strains than the essential oil. Both oil and the extract demonstrated strong inhibition on C. tropicalis at a concentration of 47.0 µg/mL (MIC).Video Clip of Methodology:CLSI microdilution broth method: 3 min 46 sec <a href="https://youtube.com/v/PBADMG2zG1c">Full Screen</a> <a href="https://youtube.com/watch?v=PBADMG2zG1c">Alternate</a>

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Chemical composition and biological activity of Nepeta cilicica

İşcan

Göğer

Demirci

et al. 2017

Bangladesh J Pharmacol

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“…Main component of Nepeta species are nepetalactones, iridoids and their glucosides, diterpenes, triterpenes and flavonoids which are responsible for biological activities such as antibacterial, antifungal and antiviral(9). …”

Section: Discussionmentioning

confidence: 99%

“…This medicinal plant is traditionally used for common cold, sinusitis and as a carminiative. Infusion provided from the aerial parts of N. satureioides is are used in folk medicine as a carminative and for cure of colds and bronchitis(91011). However, there are no scientific reports on melanogenesis inhibitory activity of N. satureioides .…”

Section: Introductionmentioning

confidence: 99%

Inhibitory effects of different fractions of Nepeta satureioides on melanin synthesis through reducing oxidative stress

et al. 2017

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Nepeta satureioides Boiss. has been used in traditional medicine of eastern countries and is famous for its medicinal properties. The aim of this study was to evaluate the effect of methanol (MeOH), n-hexane and dichloromethane (CH2Cl2) fractions of the extract on melanin synthesis and oxidative stress in B16F10 melanoma cell line. The B16F10 cell line viability after treatment with increasing concentrations of different fractions of the plant (5-60 μg/mL) was measured using MTT assay. The inhibitory effect on synthesis of melanin, mushroom tyrosinase activity, cellular tyrosinase and oxidative stress were determined by the colorimetric and fluorometric methods. The data showed that at concentrations below 60 μg/mL, fractions did not show significant toxicity on melanoma cells. The amount of melanin synthesis by MeOH and CH2Cl2 fractions and mushroom tyrosinase activity by the MeOH fraction declined in B16F10 cells. In addition to the capacity of MeOH, n-hexane and CH2Cl2 fractions in decreasing the amount of reactive oxygen species (ROS) in melanoma cells, all fractions revealed remarkable antioxidant activity. The melanogenesis inhibitory and antioxidant effects of N. satureioides on B16F10 cells may suggest this plant as a new pharmaceutical agent in reducing skin pigment and skin aging in cosmetic industry.

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“…Various types of chemical constituents such as monoterpene derivatives, sesquiterpenes, diterpenes, triterpenes, phenolic compounds such as flavonoids, phenolic acids, and some other constituents have been identified in Nepeta species (16)(17)(18). Phytochemical screening tests of N. menthoides have been shown to be positive for triterpene, sterol, saponin and flavonoid (10,19,20).…”

Section: Phytochemistrymentioning

confidence: 99%

Nepeta menthoides Boiss. & Buhse, an endemic species in Iran: A review of traditional uses, phytochemistry and pharmacology

Memariani

Rahimi

Farzaei

et al. 2019

J Herbmed Pharmacol

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Implication for health policy/practice/research/medical education:As one of the endemic species in Iran, Nepeta menthoides is widely used as medicinal plant by the vernacular name "Ostokhodus" in traditional Persian medicine. Reviewing the scientific evidence via collecting, classifying and summarizing published studies on the medicinal properties and possible side effects of this plant can be helpful for therapists and researchers in traditional medicine. It also provides basic information for further research as a coherent herbal monograph.Please cite this paper as: Memariani Z, Rahimi A, Farzaei MH, Zakaria Nejad N. Nepeta menthoides Boiss. & Buhse, an endemic species in Iran: A review of traditional uses, phytochemistry and pharmacology.

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Essential oil ofNepetagenus (Lamiaceae) from Iran: a review

Cited by 38 publications

References 42 publications

Chemical composition and biological activity of Nepeta cilicica

Chemical composition and biological activity of Nepeta cilicica

Inhibitory effects of different fractions of Nepeta satureioides on melanin synthesis through reducing oxidative stress

Nepeta menthoides Boiss. & Buhse, an endemic species in Iran: A review of traditional uses, phytochemistry and pharmacology

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