Establishing reference intervals for haematological and biochemical blood variables in Lika pramenka sheep

Abstract

Haematological and blood biochemical variables are key elements for routine assessment of animal health status, with implications in animal production and food safety. However, only reliable reference intervals of haematological and biochemical blood variables can provide the basis for accurate interpretation of the obtained blood results. Haematological and biochemical blood values critically dependent on living conditions, region, husbandry, rearing location, and diet. The aim of this study was to determine the reference intervals for selected important and informative haematological and blood biochemical variables for females of the Croatian indigenous sheep breed, Lika pramenka. We used several advanced statistical methods and assessed their applicability for determination of relevant reference intervals under conditions specific to indigenous sheep breeding. The results show that the reference intervals from the available literature are orientational but not adequate for the specific challenges encountered in raising indigenous breeds in their natural habitat. This was illustrated by the large number of clinically healthy animals with blood variable values falling outside the reference intervals given in the sources available previously.

Effects of Corn Supplementation into PKC-Urea Treated Rice Straw Basal Diet on Hematological, Biochemical Indices and Serum Mineral Level in Lambs

“…The average concentrations of hemogram and biochemical indicators in the blood of lambs remained normal at the beginning of the experiment, which is based on average values for RBC concentrations in sheep (8–13 (× 10 6 ) RBC/mL) [27]. The MCV values of the treatments were within the normal range of 23–48 fl [28].…”

“…The values of WBC, which can be used as an indicator of inflammation, were significantly different among groups. The mean concentration of WBC of the groups remained within the normal range (4000–12,000 × 10 9 /L) [27,28]. The absence of any effect on B Neuts and S Neuts indicated that the source of protein has no effect on the blood profile.…”

Reference values of blood parameters in rams of the Bosnian Pramenka breed

“…Shek Vugrovečki et al (2017) in the Lika Pramenka sheep determined normal distributions for RBC, HGB, MCV, MCH, UREA and TPROT and log normal or nonnormal distributions for other hematology and biochemistry parameters. Our results show that a large number of parameters in the tested rams do not show a normal distribution.…”

“…Blood biochemical parameters were compared with the values obtained from geographically close regions as well as from the globally recognized literature. Shek Vugrovečki et al (2017) found the following benchmarks for blood biochemical parameters in Lika Pramenka sheep: TPROT 66.7-91 g/L; ALB 35.4-47.5 g/L; UREA 6-10.9 mmol/L; TBIL 5-11 μmol/L; GLU 1.4-3.7 mmol/L; CHOL 0.74-2.7 mmol/L; and AST 110-241 IU/L. Šimpraga et al (2013) reported the following reference values for the biochemical parameters: TPROT 66.8-87.4 g/L; ALB 28.5-44.7 g/L; UREA 3.5-7.8 mmol/L; GLU 2.9-4.3 mmol/L; AST 66.2-129.3 IU/L.…”

The Effects of Common Vetch Grain (Vicia Satıva) on Some Blood, Rumen Parameters and Rumen Protozoa in Lambs

“…. Pre (A)-and post (B)-research blood sugar (BS), total protein (TP), triglycerides (TG), urea blood urea nitrogen (BUN) blood calcium (Ca), blood potassium (K), blood phosphorus (P), blood chlorine (Cl), blood sodium (Na) ( In the literature, the blood Na levels of lambs have been reported in the range of 142.38-154.09 mg dl -1 (Bórnez et al 2009; Al-dain and Jarjeis 2015) and have been reported to be affected by the Na level of the ration (Vugrovečki et al 2017). In the present study, Na levels of the lambs in the SHII group were slightly lower than those of the C and SHI group.…”