Ethanol consumption enhances periodontal inflammatory markers in rats

Dantas, Aline Maia; Mohn, Claudia; Burdet, Berenice; Zubilete, María Zorrilla; Mandalunis, Patricia; Elverdín, Juan C.; Fernández‐Solari, Javier

doi:10.1016/j.archoralbio.2012.02.008

Cited by 30 publications

(34 citation statements)

References 27 publications

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“…And Souza et al 12 also evaluated rats receiving a concentration of 20% by volume showed significantly greater alveolar bone loss in ligature-induced periodontitis in female rats 12 . Dantas et al 14 demonstrated that short-time ethanol administration increased the length of the periodontal ligament in rats submitted to ligature induced periodontitis and diminished the alveolar bone volume, which suggest that alcohol consumption promotes the progression of this disease in the short term. Differently, Irie et al 15 reported that a high dose of ethanol itself (36% of total calories in the diet) was not capable of affecting ligature-induced bone resorption.…”

Section: Discussionmentioning

confidence: 99%

“…Irie et al 15 suggest that chronic alcohol consumption increased periodontal inflammation, oxidative damage, TNF-alpha production and had an additive effect on polymorphonuclear leukocyte infiltration and gingival oxidative damage. Dantas et al 14 suggested that ethanol consumption could represent a risk indicator for periodontal disease since augments the expression of inflammatory markers in healthy rats, and increases them significantly, at short term, in the presence of disease.…”

Section: Discussionmentioning

confidence: 99%

“…Research suggests that alcohol consumption is associated with the increase of severity of periodontitis in humans [4][5]19 , periodontal inflammation [14][15] and alveolar bone loss in periodontal disease in rats [11][12][13] . However, others studies on humans have shown no relation between periodontal disease and alcohol intake [9][10] .…”

Section: Discussionmentioning

confidence: 99%

“…However, more recent studies on humans have shown no relation between periodontal disease and alcohol consumption [6][7] . The use of rat models has been applied in the evaluation of periodontal pathogenesis 8 and regarding the influence of risk indicator/factors, such as estrogen deficiency [9][10] , alcohol consumption [11][12][13][14][15][16] , nicotine 17 and simultaneous nicotine and alcohol use 18 on disease progression.…”

Section: Introductionmentioning

confidence: 99%

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Effects of alcohol intake in periodontitis progression in female rats: a histometric study

Souza¹,

Ricardo²,

Rocha³

2014

Braz. J. Oral Sci.

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Aim: To evaluate histometrically the effect of low and high caloric value of ethanol on ligatureinduced bone loss in female rats. Methods: Sixty female rats were divided into five groups of 12 animals each: Normal Control (water), Test A (low ethanol), Control A (low iso), Test B (high ethanol) and Control B (high iso). Control Groups A and B received diets with the same amount of calories consumed by Test Groups A and B, respectively, with ethanol replaced by isocaloric amounts of carbohydrate. Four weeks prior to the end of the experimental period, half of the rats in each group were randomly assigned to receive a ligature on mandibular molar, whereas the other half of group was left unligated. At 8 weeks, the animals were sacrificed, and the specimens were processed to obtain decalcified sections. The area of periodontal ligament and/or bone loss in the furcation region of the first molars was histometrically measured in five sections per specimen (mm²). Results: Ethanol intake did not have effect on the alveolar bone loss in unligated teeth (p>0.05). However, in ligature-induced periodontitis, high value of calories associated with ethanol feeding enhanced the area of bone loss (p<0.05). Conclusions: The results of this study demonstrated that a low-ethanol diet did not affect the periodontium, while a high-ethanol diet may aggravate the progression of periodontitis, as demonstrated by the increased furcation region bone destruction in periodontal disease.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effects of alcohol intake in periodontitis progression in female rats: a histometric study

Souza¹,

Ricardo²,

Rocha³

2014

Braz. J. Oral Sci.

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“…Além disso, eles verificaram que a frequência de bolsa com profundidade ≥5 mm foi maior crônico pode afetar o sistema imune ao reduzir a capacidade dos indivíduos de combater infecções, tornando-os mais propensos a serem infectados por uma variedade de agentes patogênicos. 19 Hornecker et al, por sua vez, relataram um maior risco de destruição periodontal e perdas dentárias em consumidores pesados de bebida alcóolica. 20 Os autores indicam ainda que o efeito nas doenças periodontais parece resultar de autonegligência devido ao consumo crônico deste tipo de bebida.…”

Section: (44%) Associação Entre Periodontite E Fatores Sóciodemográfiunclassified

Associação entre periodontite e fatores sociodemográficos, índice de massa corporal e características do estilo de vida

Borba

Molz

Santos

et al. 2016

Rev Epidemiol Control Infect

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Exceto onde especificado diferentemente, a matéria publicada neste periódico é licenciada sob forma de uma licença Creative Commons -Atribuição 4. //dx.doi.org/10.17058/reci.v6i4.8290 Páginas 01 de 06 não para fins de citação Justificativa e Objetivos: As doenças periodontais são bastante prevalentes na população, tornando-se fundamental a necessidade de se identificar os aspectos epidemiológicos relacionados a essas patologias. Assim, objetivou-se avaliar se características do estilo de vida, fatores sóciodemográficos e o estado nutricional estariam correlacionados à presença ou não de periodontite, bem como com a sua severidade. Métodos: Trata-se de um estudo transversal com 77 indivíduos (40-70 anos de idade), de ambos os gêneros, voluntários da clínica do Curso de Odontologia da Universidade de Santa Cruz do Sul. Realizou-se um questionário com a história médica, hábito de fumo e álcool, dados socioeconômicos e antropométricos. Clinicamente, executaram-se os exames de profundidade de sondagem, sangramento à sondagem e perda de inserção clínica de todos os dentes presentes na boca dos sujeitos da amostra que foram divididos em três grupos: saúde periodontal, periodontite moderada e periodontite severa. Resultados: A idade média dos indivíduos foi de 52,32±6,86 anos, sendo a maioria do sexo feminino. O predomínio da doença periodontal severa foi na faixa etária entre 50-59 anos, assim como entre aqueles sujeitos com sobrepeso e obesidade. O consumo de fumo e álcool foi pequeno (18% e 11%, respectivamente). Verificou-se uma associação significativa entre a periodontite e o nível socioeconômico, sendo que nas classes A-B1, a maioria dos indivíduos estava com saúde (61%), enquanto que nas classes C2-D-E, a maioria estava com periodontite severa (47%). Conclusão: A população menos favorecida financeiramente teve maior comprometimento periodontal e, mesmo havendo associação com a periodontite, às demais variáveis não apresentaram diferença significativa. Background and Objectives:Periodontal diseases are very prevalent in the population, and it is essential to identify the epidemiological aspects related to these pathologies. Thus, we aimed to evaluate whether lifestyle characteristics, sociodemographic factors and nutritional status would be correlated with the presence or absence of periodontitis, as well as disease severity. Methods: This is a cross-sectional study with 77 subjects (aged 40 to 70 years old) of both genders, volunteers at the Dentistry School Outpatient Clinic of the University of Santa Cruz do Sul. A questionnaire was applied, which included medical history, smoking habit and alcohol consumption, socioeconomic and anthropometric data. Clinically, tests of probing depth, bleeding-to--probing, and loss of clinical insertion of all teeth present in the mouth of the sample subjects were performed, after which the sample was divided into three groups: periodontal health, moderate periodontitis, and severe periodontitis. Results:The mean age of the individuals was 52.32 ± 6.86 years, with most bei...

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The Role of Nutrition in Periodontal Diseases

Quiles

Varela-López

2013

Studies on Periodontal Disease

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Ethanol consumption enhances periodontal inflammatory markers in rats

Cited by 30 publications

References 27 publications

Effects of alcohol intake in periodontitis progression in female rats: a histometric study

Effects of alcohol intake in periodontitis progression in female rats: a histometric study

Associação entre periodontite e fatores sociodemográficos, índice de massa corporal e características do estilo de vida

The Role of Nutrition in Periodontal Diseases

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