Etiology and anti-microbial sensitivity of organisms causing community acquired pneumonia: A single hospital study

Abstract

Objective:The objective of this study was to identify the common etiological pathogens causing community acquired pneumonia (CAP) in our hospital and sensitivity patterns to the common antibiotics used.Materials and Methods:This study was undertaken in a 750 bedded multi-specialty referral hospital in Kerala catering to both urban and semi-urban populations. It is a prospective study of patients who attended the medical out-patient department and those admitted with a clinical diagnosis of CAP, during the year 2009. Data were collected based on detailed patient interview, clinical examination and laboratory investigations. The latter included sputum culture and sensitivity pattern. These were tabulated and percentage incidence of etiological pathogens calculated. The antimicrobial sensitivity pattern was also classified by percentage and expressed as bar diagram.Results:The study showed Streptococcus pneumoniae to be the most common etiological agent for CAP, in our hospital setting. The other organisms isolated in order of frequency were Klebsiella pneumoniae, Pseudomonas aeruginosa, Alpha hemolytic streptococci, Escherichia coli, Beta hemolytic streptococci and atypical coli. S. pneumoniae was most sensitive to linezolid, followed by amoxicillin-clavulanate (augmentin), cloxacillin and ceftriaxone. Overall, the common pathogens causing CAP showed highest sensitivity to amikacin, followed by ofloxacin, gentamycin, amoxicillin-clavulanate (augmentin), ceftriaxone and linezolid. The least sensitivity rates were shown to amoxicillin and cefoperazone.Conclusion:In a hospital setting, empirical management for cases of CAP is not advisable. The present study has shown S. pneumoniae as the most likely pathogen and either linezolid or amikacin as the most likely effective antimicrobial in cases of CAP, in our setting.

Bacteriological and Clinical Profile of Community Acquired Pneumonia in a Tertiary Care Hospital.

“…In most of the previous studies predominant number of patients were older (>50 yrs). [8,11] Most of our patients presented with cough (95%) and fever which are same as found in previous studies.…”

“…[6,8,9] In our study we found occurrence of klebsiella around 9% and comes 3 rd after Pseudomonas(11%). One study from Srinagar found Psudomonas as commonest cause of CAP.…”

Bacterial Etiology and Antibiotic Sensitivity Pattern of Community Acquired Pneumonia in Diabetic Patients: Experience in a Tertiary Care Hospital in Bangladesh

“…Majority of the bacteria were sensitive to imipenem and amikacin which is similar to other studies. 22 No case of colistin resistance in Acinetobacter and vancomycin resistance in Staphylococcus aureus were observed in this study.…”

Surveillance data on micro-organisms in respiratory tract infections at a tertiary care teaching hospital in South India

“…Study conducted by Shalini et al (2011) 13 revealed that Klebsiella (20.3%), Pseudomonas (9.1%) and S. aureus (6.3%) were the most common organisms isolated. Menon RU et al (2013) 14 conducted a similar study and found that S. pneumonia was the most common etiological agent followed by K. pneumoniae, Pseudomonas aeruginosa. Sputum (236), Throat swab (91), Tracheal (30) were the major samples collected from patients infected with RTI during the study period.…”