Evaluating the mechanical behavior of arterial tissue using digital image correlation

Zhang, Dongsheng; Eggleton, Charles D.; Arola, D.

doi:10.1007/bf02412146

Cited by 98 publications

(45 citation statements)

References 27 publications

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“…In contrast, PRFM made of the same components in our experiments, gives an elastic modulus of 937.3 kPa. This level is comparable with that of arterial tissue (Zhang et al, 2002), and represents approximately 50% of the stiffness of intact human skin (Zhang et al, 2007). These data indicate that PRFM is more than 600 times stiffer than the stiffest fibrin clot obtained at ambient pressure and described in the literature to date.…”

Section: Discussionmentioning

confidence: 55%

A recently developed bifacial platelet-rich fibrin matrix

Lucarelli

Beretta

Dozza

et al. 2010

eCM

121

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Platelet-rich plasma (PRP) is used clinically in liquid or gel form to promote tissue repair. Because of the poor mechanical properties, conventional PRP is often difficult to handle when used in clinical settings and requires secure implantation in a specific site, otherwise when released growth factors could be washed out during an operation. In this study, we analyzed the end product of a recently developed commercially available system (FIBRINET ® ), which is a dense pliable, platelet-rich fibrin matrix (PRFM). We characterized the mechanical properties of PRFM and tested whether PRFM releases growth factors and whether released factors induce the proliferation of mesenchymal stem cells (MSC). Mechanical properties as well as platelet distribution were evaluated in PRFM. PRFM demonstrated robust mechanical properties, with a tear elastic modulus of 937.3 + 314.6 kPa, stress at a break of 1476.0 + 526.3 kPa, and an elongation at break of 146.3 + 33.8 %. PRFM maintained its mechanical properties throughout the testing process. Microscopic observations showed that the platelets were localized on one side of the matrix. Elevated levels of PDGF-AA, PDGF-AB, EGF, VEGF, bFGF and TGF-β1 were measured in the day 1-conditioned media (CM) of PRFM and growth factor levels decreased thereafter. BMP2 and BMP7 were not detectable. MSC culture media supplemented with 20% PRFM-CM stimulated MSC cell proliferation; at 24 and 48 hours the induction of the proliferation was significantly greater than the induction obtained with media supplemented with 20% foetal bovine serum. The present study shows that the production of a dense, physically robust PRFM made through high-speed centrifugation of intact platelets and fibrin in the absence of exogenous thrombin yields a potential tool for accelerating tissue repair.

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Section: Discussionmentioning

confidence: 55%

A recently developed bifacial platelet-rich fibrin matrix

Lucarelli

Beretta

Dozza

et al. 2010

eCM

121

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“…The digital image correlation that was used for the tanking test was a commercial system which had previously been used to validate LS-DYNA models of foam impact on the Orbiter wing reinforced carbon-carbon panels during the Columbia Return to Flight program [3][4][5]. Three dimensional digital image correlation has been successfully used to capture motion in a wide range of research areas from material characterization tests [6][7][8][9] to structural tests [10][11][12], to biomechanics [13][14][15][16].…”

Section: Fig 1 Cracks In the Et Foam At The Lo2 Flange On Panel 2 Dumentioning

confidence: 99%

Photogrammetry Measurements During a Tanking Test on the Space Shuttle External Tank, ET-137

Littell

Schmidt

Tyson

et al. 2012

Conference Proceedings of the Society for Experimental Mechanics Series

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On November 5, 2010, a significant foam liberation threat was observed as the Space Shuttle STS-133 launch effort was scrubbed because of a hydrogen leak at the ground umbilical carrier plate. Further investigation revealed the presence of multiple cracks at the tops of stringers in the intertank region of the Space Shuttle External Tank. As part of an instrumented tanking test conducted on December 17, 2010, a three dimensional digital image correlation photogrammetry system was used to measure radial deflections and overall deformations of a section of the intertank region. This paper will describe the experimental challenges that were overcome in order to implement the photogrammetry measurements for the tanking test in support of STS-133. The technique consisted of configuring and installing two pairs of custom stereo camera bars containing calibrated cameras on the 215-ft level of the fixed service structure of Launch Pad 39-A. The cameras were remotely operated from the Launch Control Center 3.5 miles away during the 8 hour duration test, which began before sunrise and lasted through sunset.The complete deformation time history was successfully computed from the acquired images and would prove to play a crucial role in the computer modeling validation efforts supporting the successful completion of the root cause analysis of the cracked stringer problem by the Space Shuttle Program. The resulting data generated included full field fringe plots, data extraction time history analysis, section line spatial analyses and differential stringer peak-valley motion. Some of the sample results are included with discussion. The resulting data showed that new stringer crack formation did not occur for the panel examined, and that large amounts of displacement in the external tank occurred because of the loads derived from its filling. The measurements acquired were also used to validate computer modeling efforts completed by NASA Marshall Space Flight Center (MSFC). Background

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“…Lighting rough surfaces with coherent light induce speckle pattern whose properties are modified with strain. Image processing have been used by Anwander et al (2000), Zhang et al (2002), Laraba-Abbes et al (2003) and Amodio et al (2003) using these optical properties. Image correlation techniques allow following strains of the sample.…”

Section: State Of the Artmentioning

confidence: 99%