Evaluation of anti-inflammatory and antioxidant activities of Copper (II) Schiff mono-base and Copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole

Pontiki, Eleni; Hadjipavlou‐Litina, Dimitra; Chaviara, A.Th.

doi:10.1080/14756360701841251

Cited by 64 publications

(29 citation statements)

References 32 publications

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“…The results support that in general, adducts of the type [Cu (dienXXY 2 ) (2a-5mt)] exhibit increased activity compared to the starting material of type [Cu (dienXXY 2 )]. An attempt to correlate the biological results with their structural characteristics and physicochemical parameters has been made (Pontiki et al, 2008).…”

Section: Anti-inflammatory Activity Of Schiff Basesmentioning

confidence: 99%

A review on versatile applications of transition metal complexes incorporating Schiff bases

Abu‐Dief

Mohamed

2015

Beni-Suef University Journal of Basic and Applied Sciences

448

270

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Antimicrobial Dyes Polymers a b s t r a c t Schiff bases and their complexes are versatile compounds synthesized from the condensation of an amino compound with carbonyl compounds and widely used for industrial purposes and also exhibit a broad range of biological activities including antifungal, antibacterial, antimalarial, antiproliferative, anti-inflammatory, antiviral, and antipyretic properties. Many Schiff base complexes show excellent catalytic activity in various reactions and in the presence of moisture. Over the past few years, there have been many reports on their applications in homogeneous and heterogeneous catalysis. The high thermal and moisture stabilities of many Schiff base complexes were useful attributes for their application as catalysts in reactions involving at high temperatures. The activity is usually increased by complexation therefore to understand the properties of both ligands and metal can lead to the synthesis of highly active compounds. The influence of certain metals on the biological activity of these compounds and their intrinsic chemical interest as multidentate ligands has prompted a considerable increase in the study of their coordination behaviour. Development of a new chemotherapeutic Schiff bases and their metal complexes is now attracting the attention of medicinal chemists. This review compiles examples of the most promising applied Schiff bases and their complexes in different areas.

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Section: Anti-inflammatory Activity Of Schiff Basesmentioning

confidence: 99%

A review on versatile applications of transition metal complexes incorporating Schiff bases

Abu‐Dief

Mohamed

2015

Beni-Suef University Journal of Basic and Applied Sciences

448

270

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“…The existed data correspond to copper complexes with NSAIDs drugs [9,[47][48][49] and Schiff bases [50][51][52] which could not be compared with our research. The complex formation in most of the cases did not lead to higher biological response compared to the free ligands or binary complexes with HL 1 and HL 2 .…”

Section: Interaction D•••a (å) H•••a (å) D-h•••a ( O )mentioning

confidence: 88%

Preparation and pharmacochemical evaluation of mixed ligand copper(II) complexes with triethanolamine and thiophenyl-2 saturated carboxylic acids

Boulsourani

Geromichalos

Repana

et al. 2011

Journal of Inorganic Biochemistry

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“…It and its esters are used in preparing perfumes, pharmaceuticals, and UV‐absorber as well as corrosion inhibitors for metals and mold inhibitors in soya sauce. Schiff base ligands act as good chelating agents for the transition and nontransition metal ions 1–4. Coordination of these compounds with metal ions, such as copper, nickel, and iron, often enhances their activities 5 as has been reported for pathogenic fungi 6.…”

Section: Introductionmentioning

confidence: 96%

Synthesis and genotoxicity of Schiff base transition metal complexes

Kara¹,

Avar²,

Kayraldız³

et al. 2011

Heteroatom Chemistry

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A new ONNO‐type azomethine ligand, 2,2′‐(ethane‐1,2‐diylidenedinitrilo)dibenzoic acid, (YLH2) (1) has been prepared by the condensation of 2‐aminobenzoic acid and glyoxal. The coordination compounds [Ni(YL)] (2), [Co(YL)] (3), [Cu(YL)(H2O)] (4), [Zn(YL)] (5), and [Cd(YL)] (6) of the YLH2 ligand with five transition metal ions, Ni(II) Co(II), Cu(II), Zn(II), and Cd(II) have been prepared. The structures of these new azomethine compounds are proposed on the basis of the elemental analyses, proton nuclear magnetic resonance, infrared, ultraviolet–visible spectroscopy, and X‐ray powder diffraction patterns. Elemental analyses indicate a ligand metal ratio of 1:1 in the coordination compounds. X‐ray powder diffraction parameters for [Cu(YL)(H2O)] and [Cd(YL)] compounds correspond to orthorhombic and monoclinic structures, respectively. The ligand acts as a tetradentate ligand bending through oxygen atoms of the hydroxyl groups of benzoic acid and nitrogen atoms of the azomethine groups. In addition, the ligand and its metal complexes have been studied for their possible genotoxic potential. © 2011 Wiley Periodicals, Inc. Heteroatom Chem 22:119–130, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.20665

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Evaluation of anti-inflammatory and antioxidant activities of Copper (II) Schiff mono-base and Copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole

Cited by 64 publications

References 32 publications

A review on versatile applications of transition metal complexes incorporating Schiff bases

A review on versatile applications of transition metal complexes incorporating Schiff bases

Preparation and pharmacochemical evaluation of mixed ligand copper(II) complexes with triethanolamine and thiophenyl-2 saturated carboxylic acids

Synthesis and genotoxicity of Schiff base transition metal complexes

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