Evaluation of Antioxidant Activity and Polyphenols Content of the Hydro-methanolic Extract from Saccocalyx satureioides Coss and Dur

Mehlous, Soulaf; Benchikh, Fatima; Benabdallah, Hassiba; Loucif, Karima; Kaoudoune, Chahrazed; Laouer, Hocine; Amira, Smain

doi:10.22270/jddt.v10i4.4166

Cited by 3 publications

(2 citation statements)

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“…Antioxidants are compounds that can delay or inhibit the oxidation of lipids and other molecules and by doing so inhibit the initiation and propagation of oxidative chain reactions. They act by one or more of the following mechanisms: reducing activity, free radical scavenging, potential complexation of pro-oxidant metals and quenching of singlet oxygen 16 . Nowadays, the search for newer natural antioxidants, especially of plant origin, has been increasing.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Antioxidant activities and total phenolic content of hydro-ethanol extract from Phlomis bovei De Noé areal parts

Amira

Amira²,

Benchikh³

et al. 2020

J. Drug Delivery Ther.

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The plants of the genus Phlomis are native to Turkey, North Africa, Europe and Asia. Phlomis bovei De Noé (Lamiaceae) is a rare Algerian endemic plant, commonly known as Kayat El Adjarah. The objective of this study is to quantify the polyphenol content and to evaluate the antioxidant activities of the ethanolic extract (EthE) of Phlomis bovei De Noé. The plant extract was prepared by macerating 100 g of ground material in 1000 ml of 85 % ethanol for 72 h, then the filtrate was evaporated using a rotary evaporator at a temperature of 45C and the filtrate was dried. The total content in polyphenols was determined using Folin Ciocalteu method. Flavonoid content in extracts was determined using Aluminum trichloride assay and the total content of tannins was determined according to Bate Smith method. The antioxidant activity was investigated in vitro by the DPPH (2, 2-diphenyl-1-picryl-hydrazyl), ABTS and iron chelating assays. The results indicate that the ethanol extract was rich in polyphenols and has an important capacity of scavenging the DPPH and ABTS free radical with an IC50 of 0.05 and 0.018 mg/ml, respectively. However, in the ferrous ions chelating ability test, PBEE extract showed moderate chelating activity (IC50 = 1.59 ± 0.05 mg/ml). To conclude, the obtained results may contribute to add possible scientific data to use Phlomis bovei industrially as herbal medicine and as supplementary sources for natural antioxidant drugs in food. Keywords: antioxidant activity, ethanol extract, Phlomis bovei De Noé, polyphenol content.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Antioxidant activities and total phenolic content of hydro-ethanol extract from Phlomis bovei De Noé areal parts

Amira

Amira²,

Benchikh³

et al. 2020

J. Drug Delivery Ther.

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“…The effect of A. santolinoides L. aqueous extract on GE and IT was studied in mice. 30 It was found that the extract induced a significant delay in GE and in IT. It has been established that polyphenols can relax the voluntary contractions of a variety of smooth muscles, including those found in blood vessels 31 , bladder muscles 32 , and uterine muscles.…”

Section: Pathways Of Ade-induced Intestinal Transit and Gastric Empty...mentioning

confidence: 97%

HPLC Profile and Different Pathways Involved in Achillea odorata-Induced Gastric Emptying and Intestinal Transit Delay

2024

TJNPR

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Medicinal plants have been used historically to treat a variety of human ailments in traditional methods. As gastrointestinal disorders have the potential to have a major negative impact on health and even result in death all over the world, there is increasing interest in discovering novel compounds that can effectively treat these disorders. 1 Research from the previous year concentrated on treating and preventing digestive tract disorders with traditional medicine. 2 The digestive system fulfils several vital roles that allow the body to get the nutrients it needs, such as vitamins, minerals, water, proteins, carbohydrates and electrolytes. Numerous neurotransmitters and mediators are involved in the complex process of controlling GE and IT. 3 Any disruption to those mechanisms leads to a variety of ailments, such as diarrhoea and constipation. Certain pathophysiological complications of the gastrointestinal tract are known to be influenced by dysfunction of gastrointestinal motility. 4

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Modern Trends in Analytical Techniques for Method Development and Validation of Pharmaceuticals: A Review

Sharma¹,

Singh²,

Ankalgi³

et al. 2021

J. Drug Delivery Ther.

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The process of drug development requires a suitable technique which helps the scientist to analyze the drug molecule is an accurate, precise, and easiest way. For the quantitative and qualitative estimation of drugs in analytical chemistry it is very important to identify the best method for method development. This study helps the author to understand the various analytical techniques available for the process of drug development which includes spectroscopy, chromatography, electrochemical techniques, electrophoretic, flow injection analysis, and hyphenated technique. All these methods contain different analytical process with a variety of separate techniques. Also, we discuss about the modern trend which are available, and implacable in all these methods to improve the analytical behavior of these techniques. In method development process the validation of document must be required in the form of accuracy, precision, specificity, limit of detection, linearity, and range is considered. So, this review article contains the brief summary of available analytical techniques, and the latest trend in method development, or the process of method validation, and development of method. The discussed methods in this review article were revealed by the scientist, and these techniques must require in new drug development process, which helps the person to utilize the potential of these techniques. Trend in the analytical chemistry to overcome the error in method development was necessary, and the latest trends in method development technique were useful to defeat errors in analytical techniques. Keywords: Analytical techniques, Modern trends, Process of method development, and validation.

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Evaluation of Antioxidant Activity and Polyphenols Content of the Hydro-methanolic Extract from Saccocalyx satureioides Coss and Dur

Cited by 3 publications

References 6 publications

Evaluation of Antioxidant activities and total phenolic content of hydro-ethanol extract from Phlomis bovei De Noé areal parts

Evaluation of Antioxidant activities and total phenolic content of hydro-ethanol extract from Phlomis bovei De Noé areal parts

HPLC Profile and Different Pathways Involved in Achillea odorata-Induced Gastric Emptying and Intestinal Transit Delay

Modern Trends in Analytical Techniques for Method Development and Validation of Pharmaceuticals: A Review

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