Evaluation of current practices in surgical antimicrobial prophylaxis before and after implementation of local guidelines

Impact of local guidelines and an integrated dispensing system on antibiotic prophylaxis quality in a surgical centre

“…8,9,25 However, the increased percentage of appropriate SAP after IDS and local protocol implementation was higher than in other similar studies. 7,8 The results of SAP appropriateness obtained in the postimplementation stage were better than those obtained by Skledar 9 or Talon et al 8 In the postimplementation stage, 4.4% of antibiotic prophylaxis was started after the surgical procedure. This result was better than that found by Talon et al, 8 or Frighetto et al 12 but lower than obtained by Skledar.…”

“…The results obtained in this study appear to be more conclusive than in other studies. [6][7][8][9][10][11] Similarly, when reasons for inappropriateness of SAP have been analysed, timing of antimicrobial administration has appeared to be the main cause of misuse, followed by the choice of antimicrobial agent and the length of therapy. 9,10,12 Two other reasons for SAP inappropriateness are a high variability in SAP criteria between different medical teams, even between surgeons from the same medical team, and poor organization.…”

The risk factors effecting the development of surgical site infection in orthopedic and neuro surgery patients without systemic disease

“…Özkurt ve arkadaşları çalışmalarında, hastaların %82.8'inde profilaksi süresinin gereğinden uzun tutulduğu, uygulamaların sadece %17'sinde tek doz ya da 24-48 saat ile (kardiyovasküler cerrahi için) sınırlı olduğu, %54.8'inde 48 saatten 5 güne kadar, %28'inde ise 6-10 gün sürdürüldüğü-nü bildirmişlerdir (22). Talon ve arkadaşları cerrahi profilaksi ile ilgili yapılan yanlışların %24'ünün profilaksi süresi ile ilgili olduğunu saptamışlardır (29). Gagliotti, cerrahi profilakside en sık (%41) uygulama süresi konusunda hata yapıldığını bildirmiştir (30).…”

Adherence to International Antimicrobial Prophylaxis Guidelines in Cardiac Surgery: A Jordanian Study Demonstrates Need for Quality Improvement

“…12 Despite the availability of these guidelines, recent studies assessing the current practice of prophylaxis throughout the world have shown that inappropriate antibiotic choice, excessive duration of use, and inappropriate timing of antimicrobial drugs remains a problem in surgical prophylaxis. [13][14][15][16][17][18][19][20] In an Italian teaching hospital, Motola et al (1998) found that third-generation cephalosporins were the most frequently used antibiotics both in patients undergoing clean (74.1%) and clean-contaminated (73.0%) surgical procedures. 15 The resulting costs were about 10-fold higher than estimated costs of antibiotic prophylaxis carried out according to international guidelines.…”