“…After preoperative imaging, Digital Imaging and Communications in Medicine (DICOM) formatted data are typically provided which can be read in an open source library, such as 3D Slicer ( , accessed on 23 March 2022) [ 46 , 65 , 74 , 87 ], or proprietary software, such as Mimics ( , accessed on 23 March 2022) [ 47 , 61 , 88 ] or Brainlab ( , accessed on 23 March 2022) [ 67 , 84 ]. Surface rendered models provide enormous utility due to their ease of creation, lightweight model representation, and additional modifiable visualization properties, such as color, transparency, wireframe representations, and heatmaps [ 89 ]. For performance limited devices, such as current commercially available OST-HMDs, the number of vertices used to represent a 3D virtual model needs to be limited to ensure a performant application; many groups have mentioned the simplification of their model using open source tools, such as Blender ( , accessed on 23 March 2022) and MeshLab ( , accessed on 23 March 2022) [ 61 ].…”