Evaluation of Diuretic Activity of Aqueous and Methanol Extracts of Lepidium sativum Garden Cress (Cruciferae) in Rats

Patel, Umang P; Kulkarni, M L; Undale, Vaishali; Bhosale, Ashok

doi:10.4314/tjpr.v8i3.44536

Cited by 77 publications

(55 citation statements)

References 12 publications

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“…The diuretic effect was comparable to Hydrochlorothiazide and methanol extract has an advantage of potassium conserving effect. [31] 2.6. PHYLA NODIFLORA Phyla nodiflora belongs to the family Verbenaceae.…”

Section: Diuretic Activitymentioning

confidence: 99%

A Review on Medicinal Plants Used as Diuretics From Karnataka State

Paarakh¹

2017

WJPPS

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Medicinal herbs are the significant source for treatment of number of diseases, one such is Diuretics. Mono and poly-herbal preparations have been used as diuretics. According to estimate, more than 650 mono and poly-herbal preparations in the form of decoction, tincture, tablets and capsules are from more than 75 plants that are in clinical use. There exist a large number of studies which supports the diuretic effects of traditional herbal medicines. Herbal medicine have been the most commonly prescribed medications for diuretics. They inhibit electrolyte reabsorption from the lumen of the nephron, increasing osmolarity, enhancing water and electrolyte excretion. It is important to note that there is a delicate balance between dietary sodium intake and sodium loss. If the balance is compromised and there is a greater intake of sodium into the body, but not enough sodium removal, complications of fluid overload occur, such as oedema, pulmonary oedema or high blood pressure. When there is greater removal of sodium, but not enough sodium intake, complications of fluid depletion take place, such as renal failure or reduced output of blood from the heart. The ability to induce a negative fluid balance has made diuretics useful in the treatment of a variety of conditions, particularly in hypertension and oedematous states. This review gives information about few herbal plants which are used traditionally in Karnataka as diuretics. There are a large number of studies which supports the diuretic effects of traditional herbal medicines which is presented along with chemical constituents and other pharmacological action of the plants.

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Section: Diuretic Activitymentioning

confidence: 99%

A Review on Medicinal Plants Used as Diuretics From Karnataka State

Paarakh¹

2017

WJPPS

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“…Five hours prior to the experiments, the test animals were placed into metabolic cages with withdrawal of food and water [20]. After oral administration of N 1 -(4-hydroxy benzoyl)-3-methyl-5-phenyl-4(N-4-chlorophenylazo)-1,2-diazole, the urinary output [5] of each group was recorded at different time intervals represent in Figure 3. …”

Section: Experimental Technique: (Scheme 2)mentioning

confidence: 99%

Synthesis and Biological Activity Study of Novel N1-(4-Hydroxy Benzoyl)-3-Methyl-5-Phenyl-4(N-4-Chlorophenylazo)-1,2-Diazole and Its Derivatives

Bhatt¹,

Singh²,

Kumar³

et al. 2017

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A series of sulpha/substituted derivatives of phenyl azo-1,2-diazole have been synthesized and tested as an anti-inflammatory and anti-bacterial activity in mature albino rats hind paw by taking Diclofenac sodium as standard. N 1 -(4-hydroxy benzoyl)-3-methyl-5-phenyl-4(N-4-chlorophenylazo)-1,2-diazole is synthesized by a two-step process. In the first step, synthesis of N 1 -4-chlorophenyl hydrazono-1-methyl-3-phenyl propane-1,3-dione by the reciprocal action of 1-methyl-5-phenylpropane-1,3-dione and diazonium salt solution of phenyl-chloride interacts with 4-hydroxybenzoic acid hydrazide to form the final compound. These diazoles, the heterocyclic compounds which contained electron withdrawing groups, were screened for analgesic activity by acetic acid induced writing method, and for anti-inflammatory activity carried on carrageenan-induced paw edema. The synthesized substituted Chlorophenylazo-1,2-diazole nucleus exhibited significant anti-bacterial, anti-cancer, anti-inflammatory activity, muscle relaxing and moderate activity in anti-proliferative studies.

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“…Group 4 (Test) -received aqueous extract of Centella asiatica (500mg/kg, p.o.). [14,15,16,17] Before the oral administration of test drugs, the animals were dosed/hydrated with 25 ml/kg body weight of normal saline (0.9% …”

Section: Drugsmentioning

confidence: 99%

Evaluation of Diuretic Activity of Aqueous Extract of Leaves of Centella Asiatica

Debnath¹

2017

WJPR

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Aim: The present study was undertaken to investigate diuretic effect of aqueous extracts of the dried leaves of Centella asiatica in normal rats.Centella asiatica (L.) is a perennial herb, faintly aromatic and used traditionally for various medicinal properties from ancient times.Demand for herbal formulation is growing all over the world as they are considered to be safer with fewer side effects than the synthetic 3.

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Evaluation of Diuretic Activity of Aqueous and Methanol Extracts of Lepidium sativum Garden Cress (Cruciferae) in Rats

Cited by 77 publications

References 12 publications

A Review on Medicinal Plants Used as Diuretics From Karnataka State

A Review on Medicinal Plants Used as Diuretics From Karnataka State

Synthesis and Biological Activity Study of Novel N1-(4-Hydroxy Benzoyl)-3-Methyl-5-Phenyl-4(N-4-Chlorophenylazo)-1,2-Diazole and Its Derivatives

Evaluation of Diuretic Activity of Aqueous Extract of Leaves of Centella Asiatica

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