Evaluation of Genotoxic Potential of Heavy Metal in a Proteinaceous Crop (Lens culinaris Medik) in Aspect to Cyto-morphological Parameters

Shahwar, Durre; Ansari, Mohd Ikram; Choudhary, Sana

doi:10.3923/jbs.2018.208.215

Cited by 9 publications

(1 citation statement)

References 21 publications

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“…Control plant showed no chromosomal aberrations while treated plants showed anomalies even at the lowest concentration. Occurrence of these abnormalities suggests their clastogenic, aneugenic and tubergenic effects [21] and are produced as a result of disturbances in spindle apparatus (bridges, anomalous metaphase, anaphase and telophase), chromosomal breakage (stray, fragments, micronuclei) etc [36, 37]. Hypothesis behind the occurrence of these root tip anomalies might be due to the fact that nanoparticles enter inside the plant through root tip cells, where it interferes with normal cell division and induces toxicity.…”

Section: Discussionmentioning

confidence: 99%

Toxicity assessment of anatase (TiO2) nanoparticles: A pilot study on stress response alterations and DNA damage studies in Lens culinaris Medik

Khan

Shahwar

Ansari

et al. 2019

Heliyon

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The research was targeted to investigate the effect of nano-TiO 2 (anatase) on germination, vigour index, stress enzymes and mitotic cell cycle profile in lentils ( Lens culinaris Medik.). Seed germination results indicated that TiO 2 NP (Nanoparticle) at lowest concentration promotes seed germination, vigour index and biomass; however, at higher concentrations, they showed significant reduction in growth parameters and photosynthetic pigments in concentration-dependent manner. NP treatments triggered an excessive formation of reactive oxygen species (ROS) which was evident from increased production of stress enzymes, lipid peroxidation, augmented DNA damage and aberrant mitotic cell division. The results exhibit a dose-dependent modification of NP- mediated oxidative stress and genotoxicity in lentil.

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Section: Discussionmentioning

confidence: 99%