2020
DOI: 10.1016/j.toxrep.2020.02.003
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Evaluation of genotoxic potential of peptides used in nuclear medicine (PSMA -617 and -11, and ubiquicidine 29-41) using a flow-cytometric, semi-automated analysis of micronuclei frequency in cell cultures

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“…Genotoxicity was determined during an in vitro study [53] indicating that ubiquicidin is a safe peptide for further development. When new radiopharmaceuticals enter the research pipeline, partition coefficients (log P) are used to determine and predict how radiopharmaceuticals behave in the human body.…”
Section: In Vitro Evaluationsmentioning
confidence: 99%
“…Genotoxicity was determined during an in vitro study [53] indicating that ubiquicidin is a safe peptide for further development. When new radiopharmaceuticals enter the research pipeline, partition coefficients (log P) are used to determine and predict how radiopharmaceuticals behave in the human body.…”
Section: In Vitro Evaluationsmentioning
confidence: 99%