Evaluation of prolotherapy in comparison with occlusal splints in treating internal derangement of the temporomandibular joint – A randomized controlled trial

Priyadarshini, Smita R.; Gnanam, A.; Sasikala, B.; Panneerselvam, Elavenil; Cheeman, S. Raja Sethupathy; Mrunalini, R.; Raja, V.B. Krishna Kumar

doi:10.1016/j.jcms.2020.11.004

Cited by 11 publications

(8 citation statements)

References 12 publications

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“…No que diz respeito ao uso de talas, Priyadarshini et al (22), comparou talas e proloterapia para o tratamento de DI. A proloterapia se mostrou superior, principalmente no alívio da dor.…”

Section: Autor/país/ano Objetivo Metodologia Resultadosunclassified

“…As talas ou placas oclusais são outra opção de tratamento não cirúrgico, amplamente utilizadas, principalmente em casos de bruxismo. Todavia, segundo Priyadarshini et al (22), a proloterapia seria mais eficaz no tratamento de desarranjo interno, principalmente no alívio da dor. Outro estudo verificou a ação estabilizadora da tala após artrocentese, verificando que a artrocentese isolada já se mostrou suficiente, já que a utilização da tala à noite não trouxe benefícios em relação ao reposicionamento do disco (23).…”

Section: Revisão De Literaturaunclassified

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Alternativas de tratamentos para pacientes com luxação de ATM: revisão integrativa

Nunes¹,

Machado²,

Bavaresco³

et al. 2023

Braz. J. Develop.

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Patologias musculares e articulares podem acometer a articulação temporomandibular (ATM), a luxação sendo uma delas. Caracteriza-se pelo deslocamento do côndilo mandibular em relação à localização anatômica normal na cavidade glenóide, podendo ser anterior, posterior, inferior ou superior a esta, e que acaba por comprometer o bem estar físico e psíquico do indivíduo. Apresenta diversos tratamentos: cirúrgicos, não cirúrgicos e a combinação de ambos. Este trabalho teve por objetivo revisar a literatura acerca das terapias não cirúrgicas para o tratamento da luxação de ATM. Foi realizada uma busca nas bases de dados PubMed e LilacS, onde 16 artigos foram selecionados após critérios de inclusão e de exclusão definidos. O estudo pode observar que as terapias não cirúrgicas que incluem toxina botulínica, ácido hialurônico, proloterapia, injeções de sangue autólogo e artrocentese são eficazes para o tratamento de deslocamento de disco e luxação de ATM, sendo que a artrocentese isolada ou associada ao ácido hialurônico se mostrou com efeito prolongado para a prevenção de futuras luxações, bem como mínimos efeitos adversos. Apesar das leituras, não houve um consenso sobre a melhor abordagem terapêutica, sugerindo-se a realização de mais estudos acerca do tema.

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“…No que diz respeito ao uso de talas, Priyadarshini et al (22), comparou talas e proloterapia para o tratamento de DI. A proloterapia se mostrou superior, principalmente no alívio da dor.…”

Section: Autor/país/ano Objetivo Metodologia Resultadosunclassified

Section: Revisão De Literaturaunclassified

Alternativas de tratamentos para pacientes com luxação de ATM: revisão integrativa

Nunes¹,

Machado²,

Bavaresco³

et al. 2023

Braz. J. Develop.

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“…Dextrose is the most widely used proliferant because it is inexpensive, accessible, and reliable. The techniques used in the treatment of TMJ hypermobility and dysfunction with the purpose of prolotherapy with a single injection or multiple injections and using dextrose in different concentrations have been described 5 , 6 , 9 , 22 . There is no definite protocol for prolotherapy in TMJ hypermobility.…”

Section: Discussionmentioning

confidence: 99%

“…There is no definite protocol for prolotherapy in TMJ hypermobility. Dextrose concentrations used in prolotherapy range from 10% to 50% 2 , 6 , 9 , 22 - 24 . In this study, dextrose at a concentration of 20%, which gives positive clinical results on TMJ hypermobility in the literature, was used, and positive clinical results were obtained for all patients 25 , 26 .…”

Section: Discussionmentioning

confidence: 99%

“…Results of evaluating the within-group differences between two different times Group Mean SE P-value Group 1 RCFD T0-RCFD T1 0.019235 0.005102 0.002* LCFD T0-LCFD T1 0.021882 0.004013 0.000* Group 2 RCFD T0-RCFD T1 0.018267 0.005321 0.004* LCFD T0-LCFD T1 0.029333 0.006657 0.001* Group 3 RCFD T0-RCFD T1 0.023769 0.006634 0.004* LCFD T0-LCFD T1 0.021385 0.004474 0.000* Control RCFD T0-RCFD T1 0.000467 0.001316 0.728 LCFD T0-LCFD T1 -0.000267 0.001449 0.857 (SE: standard error, T0: before treatment, T1: six months after treatment, RCFD T0: fractal dimension value of right condyle at time T0, RCFD T1: fractal dimension value of right condyle at time T1, LCFD T0: fractal dimension value of left condyle at time T0, LCFD T1: fractal dimension value of left condyle at time T1) *P≤0.05 By paired t-test. prolotherapy with a single injection or multiple injections and using dextrose in different concentrations have been described 5,6,9,22 . There is no definite protocol for prolotherapy in TMJ hypermobility.…”

Section: Sadi Memiş: Evaluation Of the Effects Of Prolotherapy On Con...mentioning

confidence: 99%

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Evaluation of the effects of prolotherapy on condyles in temporomandibular joint hypermobility using fractal dimension analysis

Memiş

2022

JKAOMS

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Objectives: Prolotherapy is a method that has gained popularity in recent years and has been reported to have positive short-term and long-term clinical results in maxillofacial surgery, especially temporomandibular joint (TMJ) hypermobility. This study aimed to evaluate the changes in the trabecular structure of mandibular condyles in patients who underwent prolotherapy due to TMJ hypermobility using the fractal analysis method. Materials and Methods: Forty-five patients who received dextrose prolotherapy at a concentration of 20% and fifteen control patients were included in the study. All patients had panoramic radiographs just before (T0) and six months after treatment (T1). The patients who received treatment were divided into three groups according to the number of prolotherapy injections. The regions of interest were selected from bone areas close to the articular surfaces of the condyles. The fractal dimension (FD) values were calculated. Results:The main effect of time on the FD value was significant [F (1, 56)=86.176, P<0.001]. This effect was qualified by a significant time×group interaction effect [F (3, 56)=9.023, P<0.001]. The decreases in FD values in all treatment groups between T0 and T1 times were significant (P=0.004). However, changes in FD values were not significant in the control group (P=0.728). Conclusion: Dextrose prolotherapy without the effect of the number of injections caused a decrease in FD values in the mandibular condyles over time.

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Evaluation of the effect of dextrose prolotherapy versus deep dry needling therapy for the treatment of temporomandibular joint anterior disc displacement with reduction: (a randomized controlled trial)

Gibaly,

Abdelmoiz,

Alghandour

2024

Clin Oral Invest

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Objective to compare the combined effect of Prolotherapy and Deep Dry Needling (DDN) versus DDN effect on relieving the symptoms of Temporomandibular joint (TMJ) anterior disc displacement. Patients and methods The clinical trial randomly allocated forty patients. The (control group) patients received four intraarticular and masseteric DDN sessions, while the (study group) patients were subjected to the exact technique followed by Prolosolution injection. The baseline preoperative measurements included Maximal interincisal opening (MIO), auscultation of the presence of clicking, and Visual Analogue Scale (VAS), which were repeated for postoperative measurements after one, two, five, and eight months. Results By the end of the study, all patients expressed apparent improvement in pain MIO and clicking. The inter- and intragroup comparison revealed that the pain score values of the control group after five and eight months were significantly higher than those of the study group. The study group demonstrated more significant MIO calibration than the control group, with insignificant differences between both groups regarding the presence of clicking at any time interval. The associations between clicking and VAS values, between clicking and MIO, and between VAS values and increased MIO were positive in the test group and negative in the control group. Conclusions Dextrose Prolotherapy and DDN were beneficial. However, Prolotherapy demonstrated more significant, sustained, and correlated long-term alleviation of symptoms and increased MIO. Clinical relevance The study assesses the sole effect of dextrose prolotherapy on relieving the signs of TMJ anterior disc displacement apart from the impact of the penetrating needle. Clinical trial registration The study was registered on www.clinicaltrials.gov (#: NCT05821985) by Ahmed Nagi Alghandour.

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Evaluation of prolotherapy in comparison with occlusal splints in treating internal derangement of the temporomandibular joint – A randomized controlled trial

Cited by 11 publications

References 12 publications

Alternativas de tratamentos para pacientes com luxação de ATM: revisão integrativa

Alternativas de tratamentos para pacientes com luxação de ATM: revisão integrativa

Evaluation of the effects of prolotherapy on condyles in temporomandibular joint hypermobility using fractal dimension analysis

Evaluation of the effect of dextrose prolotherapy versus deep dry needling therapy for the treatment of temporomandibular joint anterior disc displacement with reduction: (a randomized controlled trial)

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