Evaluation of remote results of surgical treatment of nodular endemic goiter with autoimmune thyroiditis

Abstract

L'évaluation des résultats à distance du traitement chirurgical du goître nodulaire endémique associé à la thyroïdite auto-immune Introduction. La thyroïdite auto-immune est l'un des problèmes les plus importants et les plus actuels de l'endocrinologie moderne, avec des mécanismes de développement étiologiques et pathogéniques insuffisamment étudiés. Elle se caractérise par le manque de méthodes de diagnostic objectives et fiables, de méthodes de traitement efficaces, de tactiques thérapeutiques incertaines et d'indications du choix des méthodes de traitement. Le but de l'étude. Détermination des marqueurs permettant de prédire l'évolution clinique et le choix ABSTRACT Introduction. Autoimmune thyroiditis is one of the most important problems of modern endocrinology, with inadequately studied etiological and pathogenic mechanisms of development. It is characterized by the lack of objective and reliable diagnostic methods, effective treatment methods, uncertain therapy or indications for the choice of treatment methods. The aim of the study. Determination of markers for prediction of clinical course and choice of surgery' volume in patients with nodular goiter and autoimmune thyroiditis, taking into account the oxidative, autoimmune and apoptotic processes. Material and methods. A total of 95 patients who were operated for a nodular endemic goiter on the

Predictors of Unfavorable Cource of Papillary Thyroid Carcinoma

“…As a result, mixed components may be added to the cytological smears, which contributes to the uncertainty of cytological results [49]. In AIT, the frequency of false-positive and false-negative TAPB results is higher [50,51].…”

"The Extent of Surgery for Unilateral Nodular Goiter With Compression Syndrome Against the Background of Autoimmune Thyroiditis"

“…In such cases, surgical treatment is absolutely indicated. In this case, possible options are thyroidectomy and hemithyroidectomy [1][2][3][4][5][6][7] . Thyroidectomy will eliminate the autoimmune aggression in the body, but in such cases the patient is doomed to use thyroxine preparations for life [8][9][10][11] .…”

“…The simplified approach to choose the extent of surgery, based mainly on ultrasound data, is almost the major reason for performing unjustified surgical interventions. The diagnosis of nodular goiter against the background of autoimmune thyroiditis (NGAIT) presents certain difficulties due to specific morphological and structural changes in the TG tissue [2][3][4][5][6][7] .…”

Analysis of complications of surgical treatment of patients with autoimmune thyroiditis

“…ORIGINAL RESEARCH / ОРИГІНАЛЬНІ ДОСЛІДЖЕННЯ УДК 616.441-002-097-089-168. [1][2][3][4][5][6] Автоімунний тиреоїдит (АІТ) вважають локальною (мононаправленою) патологією. Розроблено рекомендації та схеми лікування АІТ [1,2].…”

“…Хірургічне лікування АІТ застосовували лише у разі поєднання його з доброякісними чи злоякісними вузловими утвореннями у щитоподібній залозі (ЩЗ) та розвитку компресійного синдрому [6,7]. Аналіз даних літератури свідчить про високу ефективність хірургічного лікування хворих на АІТ з вираженою екстратиреоїдною симптоматикою, зокрема тиреоїдектомії [8][9][10].…”