Evaluation of Robinson\\\'s cytological grading by comparing it with modified Bloom-Richardson\\\'s histological grading for infiltrating ductal carcinoma of Breast

Abstract

Introduction: For Microscopic Grading of Infiltrating Ductal Carcinoma of Breast, various scoring systems are available in Cytology. In our present study, we have selected Robinson's scoring or grading system for comparison with Modified Bloom-Richardson's histological grading system in terms of concordance rate between both. Material and Methods: The present study is done at the Department of Pathology, GMERS Medical College-Junagadh (Gujarat, India) from January 2015 to June 2018 and includes 50 diagnosed cases of Infiltrating Ductal Carcinoma of Breast. Diagnosis is based upon both cytological & histological evaluation and includes microscopic grading, done by Robinson's System in Cytology and Elston & Ellis modification of Bloom-Richardson System in Histology. Result: Out of 50 cases, 8, 24 and 18 cases are of grade I, II and III tumor respectively on cytological evaluation and 6, 25 and 19 cases are of grade I, II and III tumor respectively on histological evaluation. The concordance rates between both systems for grade I, II and III tumor are 50.00%, 83.33% and 94.44% respectively with Absolute concordance rate of 82.00%. Conclusion: Robinson's system is easy, effective & comparable with Modified Bloom-Richardson's system. Both are helpful in Microscopic Grading of infiltrating ductal carcinoma of breast as an indicator of tumor behavior or aggressiveness.