Aims & Objectives: (1) To know about various histopathological types of ovarian lesions presented and diagnosed at our institute. (2) To study the incidence of ovarian lesions with respect to patient's age. (3) To study the frequency of ovarian lesions in terms of non-neoplastic or neoplastic, benign or malignant, unilateral or bilateral, etc. Materials & Methods: The present study was performed at the Department of Pathology, GMERS Medical College & Hospital-Junagadh (Gujarat, India) from January 2015 to December 2018 and includes 100 cases of ovarian lesions diagnosed on both clinical & histopathological basis. We have received ovarian specimens and performed routine grossing and H& E staining procedure. We have included parameters like Age wise incidence, Nature of Lesion, Frequency & Laterality in this present study. Results: Out of100 cases, 89% are unilateral and 11% are bilateral. 52% lesions are Benign Neoplasms, 44% lesions are Non-neoplastic Cysts and 4% lesions are Borderline & Malignant Neoplasms. Majority of cases (58%) belong to age group of 20-39 years. Among Non-neoplastic Lesions, Follicular Cyst is common & frequently bilateral while among Benign Neoplasms, Serous Cystadenoma is common & frequently bilateral. Conclusion: Ovarian Lesions both non-neoplastic and neoplastic include a variety of morphological features and show a particular age wise incidence. Role of histopathological evaluation remains always important in both diagnosis & management of such cases, particularly in cases of Malignant Lesions in order to save the patient's life.

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Pure primary squamous cell carcinoma (SCC) of the ovary is extremely rare. SCC can also arise in a mature cystic teratoma or dermoid cyst, in an ovarian endometrioma or in a brenner's tumor, but such malignant transformations are also quite rare. Development of SCC in a mature cystic teratoma (MCT) has been reported sporadically in less than 2% cases only. Here in our present study, we are reporting such a rare case of 65 years old postmenopausal woman who was diagnosed as having squamous cell carcinoma developed in a mature cystic teratoma of the ovary at our institute. This diagnosis was given on the basis of clinical (patient's history and examination), radiological (CT scan) and pathological (histopathology report) findings. We are also going to discuss other similar cases with review of literature. The only aim of this present study is to share our experience of such rare diagnosis with others.

Introduction: For Microscopic Grading of Infiltrating Ductal Carcinoma of Breast, various scoring systems are available in Cytology. In our present study, we have selected Robinson's scoring or grading system for comparison with Modified Bloom-Richardson's histological grading system in terms of concordance rate between both. Material and Methods: The present study is done at the Department of Pathology, GMERS Medical College-Junagadh (Gujarat, India) from January 2015 to June 2018 and includes 50 diagnosed cases of Infiltrating Ductal Carcinoma of Breast. Diagnosis is based upon both cytological & histological evaluation and includes microscopic grading, done by Robinson's System in Cytology and Elston & Ellis modification of Bloom-Richardson System in Histology. Result: Out of 50 cases, 8, 24 and 18 cases are of grade I, II and III tumor respectively on cytological evaluation and 6, 25 and 19 cases are of grade I, II and III tumor respectively on histological evaluation. The concordance rates between both systems for grade I, II and III tumor are 50.00%, 83.33% and 94.44% respectively with Absolute concordance rate of 82.00%. Conclusion: Robinson's system is easy, effective & comparable with Modified Bloom-Richardson's system. Both are helpful in Microscopic Grading of infiltrating ductal carcinoma of breast as an indicator of tumor behavior or aggressiveness.

Objective: The only objective of our present study is evaluation of the rate and major reasons of blood donor deferrals in our institute. Materials and Methods: A retrospective study was done at the blood bank, GMERS Medical College & Hospital, Junagadh (Gujarat) over a period of 4 years from January 2015 to December 2018. Donor eligibility criteria were followed according to the National guidelines for blood donation. Donors deferred were analysed according to their age, sex, type of donor, type of deferral, and reasons for deferral. Result: Of 26610 blood donors, 98.07% were eligible for donation and 1.93% were deferred. The deferral rates among male population and female population were 1.32% and11.92% respectively. Temporary deferral was more common than permanent one (52.92% vs 47.08%). Leading causes of deferral were hypertension (40.08% cases), anemia (21.98% cases) and hypotension (14.40% cases). Anemia was the commonest cause for temporary deferral, whereas hypertension was the commonest for permanent deferral. Maximum number of deferrals were observed in the age group of 36-50 years (41.25% cases). Conclusion: Rejection or Deferral play a pivot role in good and healthy donor selection. Both temporary and permanent criteria must be kept in mind while pre-transfusion screening of a blood donor. Inappropriate selection and unnecessary deferral are always hazardous in transfusion medicine, because both of them reduce the availability of healthy blood donors.