Evaluation of the analgesic effect of intracameral lidocaine hydrochloride injection on intraoperative and postoperative pain in healthy dogs undergoing phacoemulsification

Abstract

Intracameral lidocaine injection had significant analgesic effects in dogs undergoing cataract surgery. Results of this study suggest the value of intracameral lidocaine injection as an analgesic for intraocular surgery in dogs.

Evaluation of topical nalbuphine or oral tramadol as analgesics for corneal pain in dogs: a pilot study

“…An additional limitation of this study is that pain assessment in animals is highly subjective and response to pain among animals is variable. This was demonstrated by the unexpectedly low 50% rescue rate noted in the control group of this study as well as in other canine pain studies 47,48 . Multiple studies demonstrate that even with appropriate scoring systems, control groups may not always have a 100% rescue rate 34,47,48 .…”

“…This was demonstrated by the unexpectedly low 50% rescue rate noted in the control group of this study as well as in other canine pain studies 47,48 . Multiple studies demonstrate that even with appropriate scoring systems, control groups may not always have a 100% rescue rate 34,47,48 . The pain scoring system used in this study was modified from the University of Melbourne Pain Scale 49 and has been validated in several previous studies, including ocular models, where control animals were rescued at significantly higher rates than other groups 48,50,51 .…”

“…Multiple studies demonstrate that even with appropriate scoring systems, control groups may not always have a 100% rescue rate 34,47,48 . The pain scoring system used in this study was modified from the University of Melbourne Pain Scale 49 and has been validated in several previous studies, including ocular models, where control animals were rescued at significantly higher rates than other groups 48,50,51 . In the study reported here, blepharospasm proved to be the most consistent indication of pain, since no dog ever had a total subjective pain score ≥9.…”

Effects of intracameral injection of epinephrine and 2% lidocaine on pupil diameter, intraocular pressure, and cardiovascular parameters in healthy cats

“…However, the HR and MAP did not alter significantly with time and were within the physiological range for cats in all treatment groups . Similarly, intracameral injection of lidocaine and epinephrine did not alter cardiovascular parameter in dogs, and humans …”

“…In addition, there are reports showing that intracameral lidocaine is able to decrease intraoperative pain and humans with high myopia submitted to phacoemulsification. Similar results showed that intracameral lidocaine injection reduced the intraoperative isoflurane concentration and additional postoperative analgesic requirements in dogs undergoing phacoemulsification …”