Evaluation of the Burn Wound

Brownson, Elisha G.; Gibran, Nicole S.

doi:10.1016/b978-0-323-47661-4.00010-1

Cited by 14 publications

(7 citation statements)

References 78 publications

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“…However, high-voltage electrical burns require assessment for internal organ dysfunction, often in a burn or trauma center. 27 Renal dysfunction secondary to rhabdomyolysis is the most concerning complication of high-voltage electrical injury, which may be associated with hyperkalemia. Cardiac arrythmia secondary to a high-voltage injury is also possible and could be immediately fatal.…”

Section: Questions/discussion Points Partmentioning

confidence: 99%

Educational Case: Burn Injury—Pathophysiology, Classification, and Treatment

et al. 2021

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The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals.sagepub.com/doi/10.1177/2374289517715040 .1

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Section: Questions/discussion Points Partmentioning

confidence: 99%

Educational Case: Burn Injury—Pathophysiology, Classification, and Treatment

et al. 2021

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“…There are many factors affecting the body’s susceptibility to infections. Size and the deepness of burn injury come first among these factors [ 71 , 72 ]. Colonies of bacteria can be observed naturally in low concentrations—less than 10 5 colony-forming units (CFU), without causing any infection.…”

Section: Infectionsmentioning

confidence: 99%

Innate Immune System Response to Burn Damage—Focus on Cytokine Alteration

Sierawska

Małkowska

Taskin

et al. 2022

IJMS

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In the literature, burns are understood as traumatic events accompanied by increased morbidity and mortality among affected patients. Their characteristic feature is the formation of swelling and redness at the site of the burn, which indicates the development of inflammation. This reaction is not only important in the healing process of wounds but is also responsible for stimulating the patient’s innate immune system. As a result of the loss of the protective ability of the epidermis, microbes which include bacteria, fungi, and viruses have easier access to the system, which can result in infections. However, the patient is still able to overcome the infections that occur through a cascade of cytokines and growth factors stimulated by inflammation. Long-term inflammation also has negative consequences for the body, which may result in multi-organ failure or lead to fibrosis and scarring of the skin. The innate immune response to burns is not only immediate, but also severe and prolonged, and some people with burn shock may also experience immunosuppression accompanied by an increased susceptibility to fatal infections. This immunosuppression includes apoptosis-induced lymphopenia, decreased interleukin 2 (IL-2) secretion, neutrophil storm, impaired phagocytosis, and decreased monocyte human leukocyte antigen-DR. This is why it is important to understand how the immune system works in people with burns and during infections of wounds by microorganisms. The aim of this study was to characterize the molecular pathways of cell signaling of the immune system of people affected by burns, taking into account the role of microbial infections.

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“…In terms of local treatment, assessing the burn depth is one of the deciding factors. Although burns are usually classified into four depth degrees (I epidermal, IIA superficial dermal, IIB deep dermal and III full thickness), from the point of view of the surgeon the main challenge is to establish which burn will heal spontaneously within 3 weeks, because healing that takes more than 3 weeks generates hypertrophic scars and functional impairment [1]. Burns that do not heal within this period need excision and grafting.…”

Section: Introductionmentioning

confidence: 99%

Burn characterization using object‐oriented hyperspectral image classification

Parasca

2022

Journal of Biophotonics

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This paper presents a new approach based on hyperspectral imaging combined with an object‐oriented classification method that allows the generation of burn depth classification maps facilitating easier characterization of burns. Hyperspectral images of 14 patients diagnosed with burns on the upper and lower limbs were acquired using a pushbroom hyperspectral imaging system. The images were analyzed using an object‐oriented classification approach that uses objects with specific spectral, textural and spatial attributes as the minimum unit for classifying information. The method performance was evaluated in terms of overall accuracy, sensitivity, precision and specificity computed from the confusion matrix. The results revealed that the approach proposed in this study performed well in differentiating burn classes with a high level of overall accuracy (95.99% ± 0.60%), precision (97.30% ± 2.46%), sensitivity (97.23% ± 3.02%) and specificity (98.02% ± 1.98%). In conclusion, the object‐based approach for burns hyperspectral images classification can provide maps that can help surgeons identify with better precision different depths of burn wounds.

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Evaluation of the Burn Wound

Cited by 14 publications

References 78 publications

Educational Case: Burn Injury—Pathophysiology, Classification, and Treatment

Educational Case: Burn Injury—Pathophysiology, Classification, and Treatment

Innate Immune System Response to Burn Damage—Focus on Cytokine Alteration

Burn characterization using object‐oriented hyperspectral image classification

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