Evidence of hantavirus in wild rodents in Northern Ireland

McCaughey, Conall; Montgomery, W. Ian; Twomey, N.; Addley, Mark; O’Neill, Hugh J.; Coyle, P. V.

doi:10.1017/s0950268800001540

Cited by 18 publications

(16 citation statements)

References 8 publications

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“…Recently, it was found that the HFRS emerged in Bayannaoer district of Inner Mongolia might be caused by SEOV imported from the neighboring HFRS endemic areas [Zhang et al, 2009b]. Up to date, SEOVs have been found worldwide [McCaughey et al, 1996;Heyman et al, 2004Heyman et al, , 2008Easterbrook et al, 2007;Cueto et al, 2008;Weissenbacher et al, 1996;Wang et al, 2000;Reynes et al, 2003;Shi et al, 2003;Plyusnina et al, 2004]. All these studies suggested that SEOVs could spread widely and even worldwide following travel of their hosts Rattus species.…”

Section: Discussionmentioning

confidence: 99%

“…Hantaviruses show high genetic diversity as well as geographical clustering pattern of genetic variants within individual hantavirus type, such as HTNV [Zou et al, 2008a] and PUUV [Sironen et al, 2001]. In contrast, SEOV has been identified worldwide [McCaughey et al, 1996;Weissenbacher et al, 1996;Wang et al, 2000;Heyman et al, 2004Heyman et al, , 2009Plyusnina et al, 2004;Easterbrook et al, 2007;Cueto et al, 2008]. Notably, most of known SEOV variants including the majority of Chinese strains and also those from Brazil, Cambodia Egypt, France, Indonesia, Japan, North America, South Korea, and United Kingdom are genetically homogeneous [Wang et al, 2000;Reynes et al, 2003;Shi et al, 2003;Plyusnina et al, 2004].…”

Section: Introductionmentioning

confidence: 99%

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Hantaviruses in small mammals and humans in the coastal region of Zhejiang Province, China

Zhāng

Lin

Shi³

et al. 2010

Journal of Medical Virology

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To gain more insights into the epidemiology of hantaviruses in the coastal region of Zhejiang Province, China, the morbidity and mortality of hemorrhagic fever with renal syndrome (HFRS) were analyzed in two coastal areas: Cixi (hilly terrain) and Wenzhou (mountainous terrain). More HFRS cases have been reported in Cixi than in Wenzhou. Annual incidence rate of HFRS in Cixi had been on the level of approximately 1.5/100,000 from 1968 (when the first HFRS case was reported) to 2007, with the highest incidence rate of 8.54/100,000 in 1999. The annual incidence rate in Wenzhou has been relatively low, less than 0.5/100,000 since the first HFRS case was reported in 1981. A total of 461 rodents and 199 shrews were captured in these two areas. Hantavirus antibodies were detected in 16 of 241 (6.64%) Rattus norvegicus and 13 of 122 (10.66%) R. flavipectus. Interestingly, hantavirus antigens were identified in 6 of 196 (3.06%) Suncus murinus. Genetic analysis showed that partial M and S segment sequences recovered from rats in the two regions belong to Seoul virus (SEOV) and can be assigned into two genetic lineages. SEOV variants that belong to these two lineages of viruses are distributed widely in China and have been found outside China. As most trapped rodents were rats and SEOV was the only hantavirus detected, these results suggested that SEOV plays an important role in human hantavirus infections. They also reinforce the need for vigilance in preventing HFRS caused by hantaviruses in the coastal region.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Hantaviruses in small mammals and humans in the coastal region of Zhejiang Province, China

Zhāng

Lin

Shi³

et al. 2010

Journal of Medical Virology

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“…However, infection has been cleared from an infected laboratory colony of rats by use of caesarian section and seronegative fostering [61]. Seropositivity in juvenile animals is much less common than in adults and the highest antibody prevalence is generally in the oldest animals [62,63]. Bites and ®ghting have been implicated in transmission between adult rats [63,64].…”

Section: Infection In Rodentsmentioning

confidence: 99%

“…There are only three rodent species in Northern Ireland, Mus domesticus (house mouse), Apodemus sylvaticus (wood mouse) and R. norvegicus (brown rat) [153]. A survey of serological evidence of rodent hantavirus in Northern Ireland demonstrated antibodies to hantavirus in 11 (21.6%) of 51 R. norvegicus, 1 (3.2%) of 31 Apodemus sylvaticus and 17 (28.8%) of 59 M. domesticus [62].…”

Section: Hantaviruses In Northern Irelandmentioning

confidence: 99%

Hantaviruses

McCAUGHEY¹,

Hart

2000

Journal of Medical Microbiology

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111

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“…Early studies preceding the advent of serological techniques concentrated on laboratory mouse populations (Poiley 1970, Skinner & Knight 1971, Carthew & Verstraete 1978, Suzuki et al 1982. Following the wide adoption of serological techniques, the serological prevalence of selected viruses has been published for a very limited number of wild or laboratory-strain M. domesticus populations around the world (Van Vuuren et al 1990, Morita et al 1991b, McCaughey et al 1996. To date there has been no serological survey of viruses in wild house mice in the UK, although data have been reported for other rodent species endemic or introduced to the UK (Table 1).…”

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confidence: 99%

Serological survey of virus infection among wild house mice (Mus domesticus) in the UK

et al. 2007

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SummaryThe serological prevalence of 13 murine viruses was surveyed among 103 wild-caught and 51 captive-bred house mice (Mus domesticus), originating from several trapping locations in northwest England, using blood samples obtained during routine health screening of an established wild mouse colony. A high proportion of recently caught wild mice were seropositive for mouse hepatitis virus (86%), mouse cytomegalovirus (79%), mouse thymic virus (78%), mouse adenovirus (68%), mouse parvovirus (59%) and minute virus of mice (41%). Seroprevalences of lymphocytic choriomeningitis virus (LCMV), orthopoxvirus, reovirus-3 and murid herpesvirus 4 (MuHV-4, also called murine g-herpesvirus [MHV-68]) were low (3-13%), and no animals were seropositive to Sendai virus, pneumonia virus or polyomavirus. Seroprevalence in wild-caught animals that had been in captivity for over six months was generally consistent with the range found in recently caught wild animals, while seroprevalence was generally much lower in captive-bred mice despite no attempt to prevent viral spread. A notable exception to this was LCMV, which appeared to have spread efficiently through the captive population (both captive-bred and wild-caught animals). Given the known viral life cycles in laboratory mice, it appears that viral persistence in the host was an important contributing factor in the spread of infection in captivity.

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Evidence of hantavirus in wild rodents in Northern Ireland

Cited by 18 publications

References 8 publications

Hantaviruses in small mammals and humans in the coastal region of Zhejiang Province, China

Hantaviruses in small mammals and humans in the coastal region of Zhejiang Province, China

Hantaviruses

Serological survey of virus infection among wild house mice (Mus domesticus) in the UK

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