Evidence that venous hypertension causes stasis                dermatitis

Sippel, K.; Mayer, Dieter; Ballmer, Boris; Dragieva, Galya; Läuchli, Severin; French, Lars E.; Hafner, Jürg

doi:10.1258/phleb.2010.010043

Cited by 23 publications

(23 citation statements)

References 8 publications

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“…Pruritus was not associated with age, gender, body mass index or region of living, with 95% confi dence interval crossing one for all subsets. Stasis dermatitis which is a similar clinical entity has demonstrable correlation with venous insuffi ciency [11] as well. Recent histologic studies indicate utility of Gomori iron studies to differentiate stasis dermatitis from LSC, in addition to other common dermatoses, based on degree of iron staining [12].…”

Section: Discussionmentioning

confidence: 99%

Lower Extremity Venous Ablation as a Treatment Modality for Refractory Lichen Simplex Chronicus and Generalized Pruritus

Hossein¹

2018

Int J Vasc Surg Med

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Introduction: Lichen simplex chronicus (LSC) is a skin condition characterized by thick, leathery, scaly and extremely itchy patches of skin. It is a common pathology (up to 12% of population) with signifi cant effect on quality of life without any established clear etiology or treatment. Chronic venous insuffi ciency (CVI) is a progressive disease of the legs that occurs when the delicate bicuspid valves in the veins become weakened and develop refl ux. CVI has been associated with many complications including local or generalized pruritus that may lead to intractable itch-scratch cycle, leading to LSC lesions on various parts of the body. Cases: Recent development of multiple in-offi ce ablation techniques for treatment of CVI have led to the added benefi t of resolving the itch-scratch cycle, which in turn become the cure for LSC lesions. We present 6 cases with typical refractory LSC lesions whom we were able to cure after treatment of CVI using Radiofrequency ablation or Clarivein techniques. Conclusion: We recommend all primary care physicians and dermatologists to consider an underlying CVI as a potential cause for any LSC lesions or even intractable pruritus.

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Section: Discussionmentioning

confidence: 99%

Lower Extremity Venous Ablation as a Treatment Modality for Refractory Lichen Simplex Chronicus and Generalized Pruritus

Hossein¹

2018

Int J Vasc Surg Med

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“…22 The pathogenesis involves development of venous hypertension which further leads to chronic venous insufficiency. 23 The gaiter area of the leg, which extends from just above the malleolus to below the knee, is most common site of venous insufficiency ulcers; especially the medial aspect.…”

Section: Discussionmentioning

confidence: 99%

Varied presentations of cutaneous vasculitis: a case series

et al. 2020

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Vasculitis involves a wide spectrum of clinicopathological process with reactive damage to the involved blood vessels. There is loss of vessel integrity instigating haemorrhage & luminal compromise leading to ischemia and necrosis of the tissue supplied by the involved vessels. It may affect varied size and type of blood vessels at different locations. It may be primary or secondary to systemic disease. It may involve a single organ like skin or may involve different organ systems at the same time. This case series include six cases of cutaneous vasculitis affecting different organs with varied presentations. Skin biopsies of six patients with unusual presentations were studied. Their complete history, physical examinations, laboratory investigations including serology were analysed and correlated with histopathological findings. The patients presented with different duration of symptoms varying from as short as 15 days to 1 year. Skin lesions were present in all cases while cardiac manifestation was seen in one. Serology and autoimmune disease markers were negative in all cases except one. However, histopathological features were in concordance with the clinical diagnosis of vasculitis. They were further classified as vasculitis secondary to Churg Strauss syndrome, venous stasis, Henoch Schonlein purpura or leucocytoclastic vasculitis.Vasculitis though a rare disease may manifest as an acute or chronic condition. It needs timely diagnosis by histopathological examination to aid in further management. It is important to assess the clinical severity in primary and secondary vasculitis, as it determines morbidity and mortality.

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“…современная теория патогенеза хронических заболеваний вен -теория эндотелиальной дисфункции и веноспецифического воспаленияво многом объясняет развитие варикозной экземы и других изменений кожи и подкожной клетчатки [15]. венозная гипертензия, являющаяся основой для развития венозной недостаточности и запускающая каскад патологических реакций, играет основную роль в появлении изменений кожи [16]. патогенез варикозной экземы включает также изменения в микроциркуляторном русле вследствие нарушения гемокоагуляции и фибринолиза [17,18].…”

Section: патогенез варикозной экземыunclassified

Varicose Eczema: Current State of the Problem

Ivanov¹

2018

Novosti Khirurgii

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ВарИкозная экзеМа: соВреМенное состоянИе проблеМЫ тюменский государственный медицинский университет, г. тюмень, российская Федерация варикозная экзема, являясь частым дерматологическим проявлением хронических заболеваний вен, тем не менее, остается недостаточно изученной проблемой. не будучи опасным заболеванием, варикозная экзема значительно снижает качество жизни пациентов. термин «варикозная экзема», хотя и стал общеупотребительным, неоднозначен. проблема варикозной экземы является в первую очередь организационной: для эффективной диагностики и лечения требуется взаимодействие хирургов и дерматологов. до настоящего времени нет единых подходов к диагностике поражений кожи при хронической венозной недостаточности. трудности заключаются в разнообразии изменений кожи при данной патологии. предлагаемый алгоритм и критерии диагностики могут заполнить этот пробел. тактика лечения варикозной экземы в основном разработана. она включает лечение хронической венозной недостаточности (ликвидацию венозного рефлюкса с помощью операции или склеротерапии, венотонизирующую терапию, эластическую компрессию) и лечение изменений кожи (системную и топическую антимикробную терапию, глюкокортикоидную и иммуносупрессивную терапию). необходимость эластической компрессии при выраженной экссудации является предметом обсуждения. не ясен объем консервативной терапии, необходимый и достаточный для достижения ремиссии варикозной экземы в случае невозможности выполнения оперативного лечения.Заключение. требуется дальнейшее изучение преимуществ современных эндовазальных методов перед классической флебэктомией в лечении варикозной экземы.Ключевые слова: хроническая венозная недостаточность, дерматологические осложнения, варикозная экзема, дифференциальная диагностика, флебэктомия, склеротерапия, консервативное лечениеThe purpose of the review is to analyze the literature concerning varicose eczema, to reveal unsolved issues of diagnosis and current trends in the treatment of this pathology.Varicose eczema, being a frequent dermatological complication of chronic vein diseases, nevertheless remains an insufficiently studied problem. Varicose eczema is not a dangerous disease, but it significantly reduces the patients' quality of life. The term «varicose eczema», although it has become common, is ambiguous. The problem of varicose eczema is first of all an organizational one: for effective diagnosis and treatment of varicose eczema the cooperation of surgeons and dermatologists is necessary. There is no unified approach to the diagnosis of skin lesions in chronic venous insufficiency. The difficulty lies in the diversity of the skin changes in this pathology. The proposed algorithm and diagnostic criteria can fill this gap. The tactics of treating varicose eczema is mainly developed. Treatment of varicose eczema includes treatment of chronic venous insufficiency (elimination of venous reflux by surgery or sclerotherapy, phlebotonic drugs, elastic compression) and treatment of skin changes (systemic and topical antibacterial remedies, steroid and i...

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Evidence that venous hypertension causes stasis dermatitis

Cited by 23 publications

References 8 publications

Lower Extremity Venous Ablation as a Treatment Modality for Refractory Lichen Simplex Chronicus and Generalized Pruritus

Lower Extremity Venous Ablation as a Treatment Modality for Refractory Lichen Simplex Chronicus and Generalized Pruritus

Varied presentations of cutaneous vasculitis: a case series

Varicose Eczema: Current State of the Problem

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