Like any other business organizations, higher education institutions have been infiltrated with staff instability and mobility. Today HEIs have invested in staff development to acquire promotional levels in terms of ranking and total quality management purposes; however, staff turnover has turned the whole idea into a normal routine. This is evidenced in the big vacuums that most institutions experience, hence posing a bigger challenge to both the stakeholders and customers whereby staff are unstable at work due to several reasons that range from salary increment and globalization issues. Meanwhile, many organizations like consultancies and other universities especially in Africa compete for the fewer staff available with high academic qualifications, hence causing moonlighting and inability to customize staff sustainability and talent development. Thus, this paper is intended to review the literature using meta-analysis and analyze the likely causes and measurements that can be put in place to curtail this bizarrely situations of staff turnover in HEIs.