Examining the effect of dl-3,4-methylenedioxymethamphetamine (MDMA) and methamphetamine on the standardized field sobriety tests

The Effects of Dextromethorphan on Driving Performance and the Standardized Field Sobriety Test

“…The SFST has been a valid and reliable method to differentiate between blood alcohol concentrations above and below 0.08 percent . However, only a few studies have assessed the SFSTs sensitivity or specificity to determine individuals’ fitness to drive under the influence of illicit, prescription, and over‐the‐counter drugs . Future studies should be focused on examining and quantifying the effects of other over‐the‐counter medications on driving performance.…”

Amphetamine-type stimulant use and the risk of injury or death as a result of a road-traffic accident: A systematic review of observational studies

“…Several well-designed, placebo controlled driving simulator studies have indicated a dose-dependent association between some amphetamine-type substances, such as methamphetamine and dexamphetamine (Silber et al, 2005) and accident risk, however other studies have noted no association for other amphetamine derivatives (Brookhuis et al, 2004). Other on-road studies have similarly noted deficits in measures of lane deviation and speed maintenance abilities after administration of 3,4-methylenedioxymethamphetamine (MDMA) (Ramaekers et al, 2006), and behavioural assessments of impairments have yielded similar deficits for this substance (Downey et al, 2012).…”

“…Stough, C., Downey, L.A., King, R., Papafotiou, K., Swann, P., Ogden, E., 2012. The acute effects of 3, 4-methylenedioxymethamphetamine and methamphetamine on driving: a simulator study.…”

Recreational 3,4-methylenedioxymethamphetamine or ‘ecstasy’: Current perspective and future research prospects

“…In acute dosing studies, MDMA has been observed to impair various aspects of driving ability, including overall driving performance, and signalling adherence (Stough et al, 2012); these studies need to be repeated with chronic users. Furthermore it also changes other aspects of ocular activity, with increasing nystagmus (Downey et al, 2012), and driving problems such as tailgating are more apparent in abstinent ecstasy/MDMA consumers (Dastrup et al, 2010). Recent studies in our laboratory have failed to identify any deficits among abstinent ecstasy consumers on motion processing tasks in the context of simulated driving, such as estimation of time to collision with oncoming traffic (Bernard, 2011).…”