Experimental carcinogenesis of pyrolysis fuel oil

Human health‐based soil cleanup guidelines for diesel fuel no. 2

“…There are numerous studies describing the carcinogenic potential of petroleum hydrocarbons, including diesel fuel (Smith et al, 1951;Hueper and Ruchhoft, 1954;Shubik and Saffiotti, 1955;Shapiro and Getmanets, 1962;Saffiotti and Shubik, 1963;Getmanets, 1967;Weil and Condra, 1977;Bingham and Barkley, 1979;Grimmer et al, 1982;Nesnow et al, 1982;Doak et al, 1983;Gradiski et al, 1983;Lewis, 1983;Blackburn et al, 1984;Coomes and Hazer, 1984;Haider et al, 1984;Kane et al, 1984;Karimov et al, 1984;Lewis et al, 1984;Cragg et al, 1985;Blackburn et al, 1986;Dutcher et al, 1986;Karimov et al, 1986;NTP, 1986;Witschi et al, 1987;Biles et al, 1988;Gerhart et al, 1988;API, 1989;McKee et al, 1989aMcKee et al, , 1989b. We have reviewed these studies and selected those that provide relevant data concerning the potential carcinogenicity of diesel fuel and middle distillates.…”

Tar and Pitch

“…The experimental generation of skin carcinomas by the topical application of tars, tar fractions such as creosote, anthracene oil, and pyrolytic oil [93] of naphtha, and tar pitch is well documented [88,94]. Case reports and epidemiological studies have provided sufficient experience about the occurrence of skin, scrotum, bladder, and other systemic cancers in exposed workers [88, pp.…”