Experimental Evaluation of a New Implant Material in Frontal Sinus Obliteration: A Preliminary Report

Frontal sinus obliteration

“…7 The gold-standard material for obliteration seems to be the fat autograft, as reflected upon by Weber et al this material has the largest experimental base. [7][8][9][10][11] Other autogenic materials, including muscle, 12 corticocancellous bone, 13,14 and inorganic materials such as hydroxyapatite cement, 15 bioactive glass 16 and proplast, 17 have also been used. The inorganic materials seem to have good experimental results on animal models but have yet to be proven on human models.…”

Definitive Treatment of Persistent Frontal Sinus Infections: Elimination of Dead Space and Sinonasal Communication

“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14] Fat, muscle, bone, local flaps, and sundry alloplasts have been used as obliterative materials, with autologous tissues preferred over alloplasts, and cancellous bone and local flaps preferred over abdominal fat. 6,7,10,12,13,[15][16][17][18][19][20][21][22][23][24][25][26] Complications of a failed obliterated sinus result from inadequate removal of the frontal sinus mucosa and improper partitioning of the upper aerodigestive system from the anterior cranial base. 3,11,[27][28][29] Brain abscesses, subdural empyemas, and meningitis are rarely encountered but prove the deleterious outcomes of improper fracture management.…”

Frontal Sinus Obliteration With Hydroxyapatite Cement

“… 9 Frontal sinus obliteration with homologous tissues, such as banked lyophilized cartilage or bone, have been reported but are no longer considered options because of the risk of disease transmission. 10 Synthetic materials, including polytetraflouroethylene 11 and methylmethacrylate, 12 have been used but largely discarded. The failure of synthetic materials to become vascularized and fully integrate with native tissues results in their high percentage of infection and extrusion.…”