Experimental Studies on Fracture Healing

Benfer, J

doi:10.1001/archsurg.1973.01350180072021

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1974

1982

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Cited by 9 publications

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Collagen sponge: Theory and practice of medical applications

Chvapil

1977

J. Biomed. Mater. Res.

213

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Theoretical as well as practical-clinical applications of one form of collagen (collagen sponge) as a biodegradable material is reviewed. The role of porosity of the sponge and surface characteristics of the meshwork in relation to cell ingrowth are considered essential features of collagen sponge. Rate of resorption and antigenicity could be controlled by graded crosslinking of collagenous framework. Four basic examples of clinical use of collagen sponge are presented: as wound (burn) dressing material, as a matrix, for bone and cartilage repair, as an intravaginal contraceptive diaphragm, and as surgical tampons.

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Collagen sponge: Theory and practice of medical applications

Chvapil

1977

J. Biomed. Mater. Res.

213

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Considerations on manufacturing principles of a synthetic burn dressing: A review

Chvapil

1982

J. Biomed. Mater. Res.

114

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This review presents various considerations on the construction of a synthetic burn dressing, based mainly on collagen protein. Membranous wound covers are compared with sponge-felt types, monocomponental with composite. The importance of collagen crosslinking agent and the nonextractibility of any component from the dressing material are discussed. According to the type of the burn the dressing should be used dry or wet, plain or medicated, and changed often to reduce substantially the presence of necrotic tissue, inflammatory cell of the granulation tissue, and bacterial contamination.

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