EXPERIMENTAL STUDIES ON THE EFFECT OF<i>GLYCYRRHIZA GLABRA</i>

Shihata, I. M.; Elghamry, M. I.

doi:10.1055/s-0028-1100215

Cited by 7 publications

(3 citation statements)

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“…(clove), Saussuria lappa Clark, Aquilaria agallocha Roxb., Atractylis ovata Thunb., menthol, Borneo camphor, and Angelica anomala Lallem. The scientific reports of some Ya-hom's ingredients have shown that licorice (Hakanson et al, 1973;Takagi and Harada, 1969;Yu, 1976;Shihata and Elghamry, 1963), Saussuria lappa Clark (Yoshikawa et al, 1993), Acorus gramineus Soland (Zhang et al, 1981) and…”

Section: Introductionmentioning

confidence: 97%

Effects of Ya-hom on the gastric secretion in rats

Suvitayavat

Kodchawongs

Thirawarapan

et al. 2004

Journal of Ethnopharmacology

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Section: Introductionmentioning

confidence: 97%

Effects of Ya-hom on the gastric secretion in rats

Suvitayavat

Kodchawongs

Thirawarapan

et al. 2004

Journal of Ethnopharmacology

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“…The inhibitory effect of the extracts of Allium sativum on the uterus of non pregnant guinea pigs may be due to the presence of phytoestrogens in this plant. This supposition was previously proved in other plants like alcoholic extract of Glycyrrhiza glabra which produced inhibition of uterine motility in mice (2). On the other hand, Table 1 and Fig.…”

Section: Discussionmentioning

confidence: 89%

Biological Activities of Allium Sativum

Abdo

Al-Kafawi

1969

Japanese Journal of Pharmacology

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Allium sativum (Garlic) is a cultivated vegetable. Al-Rawi and Chakravarty (1) in dicated the therapeutic use of the bulb and juice of this plant. Actually the bulb is used in various forms of ulcers and regulation of the menstrual cycle. The juice is also used as a rubefacient in skin diseases and external ottitis and as a lotion for washing the wounds and ulcers. In addition to the wind-breaking and helminthic effect, the juice showed an improvement of the urinary secretion and sweating and an antipyretic effect in the patient with an intermittent fever. Thus, the main therapeutic indications of the juice as a syrup are diaphoretic, diuretic and expectorant effects. Inspite of the wide therapeutic availabi lity, the biological activity of this plant is little known. Therefore, in the present experi ments the effects of water and alcohol extracts of Allium sativum on the various organ func tions were observed. MATERIALS AND METHODSWater extract : The respective 20 g of the dried stems and leaves of Allium sativum in 50 ml of water was boiled for 15 minutes and the filterates was used as a water extract.Alcoholic extract: Alcoholic extract was prepared by using soxhlet apparatus for hours. Twenty gramms of the dried stems and leaves were used.Water and alcoholic extracts were prepared also from the fleshy bulb of Allium sativum by the same procedures.Experiments were performed to study the effect of water and alcoholic extracts of Allium sativum on isolated uterus and intestine as well as on the arterial blood pressure, iso lated mammalian heart and respiration.To demonstrate the effect of Allium sativum extracts on the uterus and intestine of guinea pigs, an electrically heated glass jar bath was used. The horns of the uterus were carefully dissected from freshly-killed pregnant and non-pregnant guinea pigs. Pieces from the horns of the uterus (about 4 cm long) were suspended in oxygenated Dale's solu tion of a 38°C Constant temperature. The inner vessel was of 50 ml in capacity . The normal uterine motility was recorded by a light lever on a smoked drum paper which was moving at a slow speed. The tested solutions from the leaves, stems and bulb (2 ml from water or alcoholic extracts) were added to the bath containing the piece of the uterus. The response was recorded. The same technique was applied for the intestine. Pieces of 5 cm long from the doudenum of freshly-killed guinea pigs were suspended in oxygenated Tyrode's solution. They were examined in the same way as in the uterus (2).

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“…There are conflicting reports on the effect of licorice on the cardiac function. These indicate that licorice decreased (Shihata and Elghamry, 1963;El-Mahdy et al, 1973) and increased blood pressure (Hano et al, 1950), stimulated and depressed myocardium function, and caused vasoconstriction and vasodilatation in a concentration dependent manner (El-Mahdy et al, 1973). Most Ya-hom recipes are composed of both cardiovascular stimulatory and inhibitory herbal medicines, so it is possible that Ya-hom can both decrease and increase blood pressure.…”

Section: Treatmentmentioning

confidence: 94%