Extraction optimization, characterization and antioxidant activity of polysaccharide from Gentiana scabra bge

Polysaccharides with immunomodulating activity from roots of Gentiana crassicaulis

“…These two fractions contain the same types of monosaccharides, while they are quite different in their content. The monosaccharide compositions of polysaccharides obtained from "Qin-Jiao" were distinct from those isolated from "Longdan", withCheng et al (2016) reporting the presence of fucose in addition to Gal, GalA, Ara and Rha, and the polysaccharides isolated by containing high proportions of Man and Glc. GCP-II-I constitutes lowest amount of total neutral monosaccharides (75.9%), but higher amount of acidic monosaccharides (24%) than GCP-I-I.…”

“…Size exclusion chromatography using dextran as standards was applied to determine the average molecular weight of polysaccharide fractions obtained, the results indicated that fraction GCP-I-I has higher Mw than GCP-II-I. The Mw these two fractions were higher than polysaccharides from "Longdan" (38 kDa, 28 kDa and 58 kDa) (Cheng, et al, 2016;Cai, et al, 2016). The fraction GCP-II-II has the lowest Mw (35.9 kDa) among the fractions obtained from G. crassicaulis.…”

“…Pectin, a group of polysaccharides, has been reported with various biological activities, such as antioxidant (Zhao et al, 2015;, immunomodulating (Yamada & Kiyohara, 2007), anticancer (Zong, Cao, & Wang, 2012) and antiulcer effects (Austarheim et al, 2012a). The polysaccharides from "Longdan" have shown various biological activities, such as anticoagulant (Cai, et al, 2016), antioxidant (Cheng, et al, 2016) and immunological activity (Wang, Wang, Su, & Zhang, 2014). The purified polysaccharides isolated from "Longdan" were partial characterized by GC and FT-IR; the results indicated these polysaccharides were pectic polysaccharides.…”

Metabolomics Combined with Multivariate Statistical Analysis for Screening of Chemical Markers between Gentiana scabra and Gentiana rigescens

“…According to phytochemical research, the main constituents of GRR are iridoids, xanthones, flavonoids, triterpenoids, and others [4,[9][10][11]. Arrays of studies demonstrated that iridoids and xanthones were the active components and had various remarkable pharmacological activities including hepatoprotective [12], anti-inflammatory [13][14][15], antioxidant [8,16,17] and immunomodulatory activities [17]. However, investigations into the chemical profiling of GRR and screening of chemical markers of GRR derived from the different sources remain inadequate.…”

Extração e purificação de compostos bioativos de cubiu ("Solanum sessiliflorum'), camu-camu ("Myciaria dubia") e araçá-roxo ("Psidium myrtoides") utilizando filtração por membranas com e sem promotores de turbulência

“…O tempo de extração é um fator significativo que pode influenciar o rendimento da extração sendo este parâmetro dependente do método de extração uma vez que tempos longos elevam o custo do processo e, no outro extremo, tempos curtos possuem baixos rendimentos (Horžić et al, 2009;Plaza, 2013;Domingues et al, 2014;Cheng et al, 2016).…”