Extramedullary plasmacytoma of the sphenoid sinus presenting with visual loss: A case report

Sharifi, Sara; Asadi, Mahboobe

doi:10.1002/ccr3.5758

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Cited by 3 publications

(1 citation statement)

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“… [11] M 41 Sphenoid+Clivus Headaches, diplopia, strabismus XRT 50 Gy LC (3) Sharifi et al. [12] F 62 Sphenoid Ptosis, headaches Transsphenoidal cytoreductive+XRT LC (6) Miller et al. [13] M 47 Sphenoid sinus Headaches XRT 64 GY LC (62) Marais et al.…”

Section: Discussionmentioning

confidence: 99%

Solitary plasmacytoma of the skull base: A case report and literature review

mansouri,

elouaouch,

el youssi

et al. 2023

Radiology Case Reports

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Section: Discussionmentioning

confidence: 99%

Solitary plasmacytoma of the skull base: A case report and literature review

mansouri,

elouaouch,

el youssi

et al. 2023

Radiology Case Reports

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Extramedullary plasmacytoma of the sphenoid sinus presenting with visual loss: A case report

Sharifi

Asadi

2022

Clinical Case Reports

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A rare case of sphenoid plasmacytoma in a 62‐year‐old woman who was presented with a frozen eye is reported. It was histopathologically confirmed based on transsphenoidal biopsy. Moreover, initial evaluation ruled out systemic dissemination of the disease and solitary plasmacytoma was diagnosed. Surgical removal of the tumor with complementary radiotherapy was performed as a treatment modality.

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Sphenoid plasmacytoma as initial presentation of multiple myeloma—case report

Chadli,

Oudrhiri,

Maamar

et al. 2024

Journal of Surgical Case Reports

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Plasmacytoma is a rare plasma cell neoplasm. Whether solitary or associated with multiple myeloma (MM), it rarely involves the skull base, particularly the sphenoid bone. We present a unique case of sphenoid bone plasmacytoma secondary to MM, highlighting diagnostic and therapeutic challenges. A 56-year-old female presented with headaches, vomiting, epistaxis, and cranial nerve deficits. Cerebral imaging revealed a 65-mm tumor infiltrating the sphenoid bone and adjacent structures. Subtotal resection was performed using an endoscopic nasal approach. Histopathology revealed plasmacytoma, and diagnostic workup confirmed MM. By the end of biological exploration, relapse of the sphenoid plasmacytoma was observed, and the patient was successfully treated with radiotherapy, immunochemotherapy, and autologous stem cell transplantation. After 18-month follow-up, sustained complete remission was confirmed. Although rare, the diagnosis of plasmacytoma should be considered in cases of skull base tumors. This localization is highly predictive of MM, warranting comprehensive investigations to initiate prompt and adequate management.

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Extramedullary plasmacytoma of the sphenoid sinus presenting with visual loss: A case report

Cited by 3 publications

References 16 publications

Solitary plasmacytoma of the skull base: A case report and literature review

Solitary plasmacytoma of the skull base: A case report and literature review

Extramedullary plasmacytoma of the sphenoid sinus presenting with visual loss: A case report

Sphenoid plasmacytoma as initial presentation of multiple myeloma—case report

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