Extranodal natural killer/T‐cell lymphoma nasal type in a western population: Molecular profiling identifies new therapeutic targets

Abstract

(A) Correlation matrix of unsupervised co‐regulated genes, based on the 208 genes included in the NanoString platform. Some of the clusters of co‐regulated genes corresponded to the following: Inflammatory cells; Epstein–Barr virus; B‐cells; Cytotoxic T‐cells; T‐cells; and Proliferation. (B) Analysis of genomic alterations by targeted sequencing. Distribution of mutations in the 62 analyzed genes. Rows correspond to sequenced genes, columns represent individual patients. Color coding: green, missense; blue, synonymous; pink, frameshift; violet, Indel; red, stop gained; yellow, UTR.