Extranodal non-Hodgkin's lymphoma of the head and neck

Wulfrank, D; Speelman, Thierry; Pauwels, Carlos; Roels, H; Schryver, A. De

doi:10.1016/s0167-8140(87)80243-8

Cited by 41 publications

(28 citation statements)

References 19 publications

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“…The majority of the patients had tumors which belonged to the aggressive histological varieties, particularly diffuse large cell and immunoblastic lymphomas. These results are in accordance with those reported by other [3,6,[9][10][11][12][13], A few comments, however, are warranted. First, in the pre sent series strict criteria were employed to distinguish extranodal from nodal lymphomas.…”

Section: Discussionsupporting

confidence: 92%

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Primary Extranodal Non-Hodgkin’s Lymphoma of the Head and Neck

Economopoulos

Asprou²,

Stathakis³

et al. 1992

Oncology

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Among 387 cases of non-Hodgkin’s lymphoma (NHL) treated in our units between January 1977 and December 1990, 52 (13.4%) had primary extranodal (PE) NHL of the head and neck. The median age was 55 years with a M:F ratio of 1.9:1. The most frequent primary site was the tonsil (28 cases), followed by oral cavity, parotid gland, orbit and other sites. The aggressive histological subtypes predominate. 55.2% of the patients were in stage I and 44.8% in stage II of disease. The CR rate was high (94.2%). The 5 years’ overall survival rate was 65% and it was influenced mainly by stage (stage I 82.5% vs. 48.7% in stage II). Sex, age and histology did not significantly affect survival rate. Patients with primary Waldeyer’s ring involvement (WR group) did not differ significantly from the other primary sites analyzed as a group (non-WR group) in respect to median age, sex distribution, histology and CR rates. They differed, however, in: (1) stage distribution with stage II disease more frequent in the WR group; (2) overall survival and disease-free survival both of which were significantly better in the non-WR group; and (3) the high incidence of GI tract involvement as initial manifestation of relapse in the WR group. It is concluded that the behaviour of the Waldeyer’s ring PE-NHL is rather distinctive and should be considered separately from the other PE-NHL of the head and neck.

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Section: Discussionsupporting

confidence: 92%

“…Patients in stage I had a better outcome than pa tients in stage II disease. The importance of stage has been stressed repeatedly in the literature [3,9,13] but differences in survival between stages I and 11 was not statistically sig nificant in all the reported series [6].…”

Section: Discussionmentioning

confidence: 99%

Primary Extranodal Non-Hodgkin’s Lymphoma of the Head and Neck

Economopoulos

Asprou²,

Stathakis³

et al. 1992

Oncology

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“…This incidence matches those of single-center retrospective studies published since 1986: 1.9 to 11.4 cases per year [2][3][4][5][6][7][8][9][10][11][12][13].…”

Section: Discussionsupporting

confidence: 84%

Extranodal lymphoma of the head and neck: A 67-case series

Picard

Cardinne

Denoux

et al. 2015

European Annals of Otorhinolaryngology, Head and Neck Diseases

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“…[10] It presents in extranodal sites in 40% of cases where the gastrointestinal tract is the most common site occurring in over 50% of patients, followed by the head and neck regions (11-33%). [11] The most recent World Health Organization (WHO) classification of lymphoma subdivides lymphomas based on cellular origin: B cell lymphomas, T cell lymphomas, natural killer lymphomas, and Hodgkin's lymphoma. [12] MALT lymphomas represent approximately 8% of all non-Hodgkin's lymphomas.…”

Section: Section: Dentistry Discussionmentioning

confidence: 99%

Diffuse Swelling of Salivary and Lacrimal Glands as a First and only Manifestation of Non-Hodgkin B-Cell Lymphoma: A Case Report

Eltayeb¹,

Alfadul²,

Agaimy³

et al. 2016

AIMDR

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Lymphoma is the third most common cancer worldwide. Oral cavity Lymphoma forms 3% of all lymphomas in the general population. This is a case report of non Hodgkin B-cell lymphoma in 60 -year-old black male who was diagnosed earlier as having benign lympho-epithelial lesions of salivary and lacrimal glands. The patient was complaining of painless symmetrical facial swelling of the parotid, submandibular and lacrimal glands. Serological findings were negative for antinuclear antibody (ANA), anti-SS-A and anti-SS-B antibodies. Bilateral surgical excision of disfiguring buccal swollen salivary gland revealed a B-cell lymphoma. Chemotherapy started and dramatic response was noticed with total disappearance of all lacrimal and salivary gland swelling.

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Extranodal non-Hodgkin's lymphoma of the head and neck

Cited by 41 publications

References 19 publications

Primary Extranodal Non-Hodgkin’s Lymphoma of the Head and Neck

Primary Extranodal Non-Hodgkin’s Lymphoma of the Head and Neck

Extranodal lymphoma of the head and neck: A 67-case series

Diffuse Swelling of Salivary and Lacrimal Glands as a First and only Manifestation of Non-Hodgkin B-Cell Lymphoma: A Case Report

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