Fabrication and characterization of 1D brushite nanomaterials via sucrose ester reverse microemulsion

Abstract

In the present study, 1-dimensional (1D) brushite nanomaterials were fabricated through sucrose ester based reverse microemulsion for the first time. X-ray diffraction patterns revealed that the nanomaterials possessed brushite crystal phase with trace amount of hydroxyapatite. The size and morphology of brushite crystals were governed by the changes in the aqueous-to-sucrose ester weight ratio at low initial reactant concentration, giving rise to rod-like and fibre-like 1D nanomaterials. Brushite nanorods and nanofibres with average diameters of 25.53 AE 4.60 nm (aspect ratio $ 6) and 76.18 AE 19.74 nm (aspect ratio $ 40), respectively, had been synthesized. As the reactant concentration increased, it became the key factor in controlling nucleation and crystal growth, rendering the aqueous-to-sucrose ester ratio unimportant. Formation mechanism of various morphologies of brushite crystals is postulated. #

Nanodimensional and Nanocrystalline Calcium Orthophosphates

“…They form stable colloidal solutions displaying minimal agglomeration [538]. Nano-sized rods and nanodimensional fibers of DCPD with average diameters of 25 ± 5 nm (aspect ratio ~ 6) and 76 ± 20 nm (aspect ratio ~ 40), respectively, were synthesized by sucrose ester based reverse microemulsion technique [539]. A similar approach was used in another study [431].…”

Effects of platelet‐rich plasma on biological activity and bone regeneration of brushite‐based calcium phosphate cement

“…Subsequently, degradation rate was increased in B-P3 through the dissolution of DCPD crystals. 32 The dissolution of DCPD crystals released more Ca and P ions which combined with other ion from microenvironment produced characteristics apatite phase on B-P3 surface similar to bone apatite. 33,34 Similarly, incorporating carbonate into the biological apatite with a nonstoichiometric Ca/P ratio is the principle mechanism for carbonated apatite formation.…”

“…In contrast, faster reaction occurred in B‐P3 and increased reactant concentration into the microenvironment. Subsequently, degradation rate was increased in B‐P3 through the dissolution of DCPD crystals . The dissolution of DCPD crystals released more Ca and P ions which combined with other ion from microenvironment produced characteristics apatite phase on B‐P3 surface similar to bone apatite .…”

Smart designing of new hybrid materials based on brushite-alginate and monetite-alginate microspheres: Bio-inspired for sequential nucleation and growth

“…These phosphates are usually synthesized in an aqueous medium by double decomposition of a calcium salt and a phosphate salt or by neutralization of phosphoric acid in lime [36,37]. Other routes have been also explored to synthesis these calcium phosphates such as sol-gel [38], solid state [39], chemical precipitation [40], hydrothermal [41], hard templating [42], flame-spray route [43], dual irradiation of the microwave and ultrasound [44], and physiological conditions [45]. More recently, Gomez-Morales et al have controlled the precipitation of calcium phosphate such as brushite by using vapor diffusion method in microdroplets and amino acids like organic additives [46].…”