Fabrication and measurement of a fiber optic localized surface plasmon resonance sensor chip for molecular diagnostics

Kim, Hyeong-Min; Park, Jae‐Hyoung

doi:10.1016/j.sna.2021.112982

Cited by 6 publications

(2 citation statements)

References 46 publications

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“…In these FOSPR sensors, SPR on the outer surface of the metal film is excited by the principle of total internal reflection in fiber, enabling the realtime and highly sensitive detection of the ambient surroundings by demodulation of the optical signals such as wavelength, the intensity around the resonance wavelength, and others [9]. Moreover, various functional materials such as nanoparticles [10,11], multilayer metal/dielectric layers [12,13], graphene [14,15], and polymers [16] are integrated on the surface of FOSPR sensors to improve their sensitivity and tunability, further expanding their practical applications. In addition, tilted fiber Bragg grating SPR sensors [17][18][19], as another common FOSPR sensor, can achieve SPR on the outer surface of metal film without removing cladding by the diffraction effect of tilted grating, exhibiting a wide range of applications in various detection fields such as disease biomarkers, heavy metal pollution, and the like.…”

Section: Introductionmentioning

confidence: 99%

Plasmonic Resonance Coupling of Nanodisk Array/Thin Film on the Optical Fiber Tip for Integrated and Miniaturized Sensing Detection

Wei

et al. 2023

Sensors

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Fiber-optic surface plasmon resonance (FOSPR) sensing technology has become an appealing candidate in biochemical sensing applications due to its distinguished capability of remote and point-of-care detection. However, FOSPR sensing devices with a flat plasmonic film on the optical fiber tip are seldom proposed with most reports concentrating on fiber sidewalls. In this paper, we propose and experimentally demonstrate the plasmonic coupled structure of a gold (Au) nanodisk array and a thin film integrated into the fiber facet, enabling the excitation of the plasmon mode on the planar gold film by strong coupling. This plasmonic fiber sensor is fabricated by the ultraviolet (UV) curing adhesive transferring technology from a planar substrate to a fiber facet. The experimental results demonstrate that the fabricated sensing probe has a bulk refractive index sensitivity of 137.28 nm/RIU and exhibits moderate surface sensitivity by measuring the spatial localization of its excited plasmon mode on Au film by layer-by-layer self-assembly technology. Furthermore, the fabricated plasmonic sensing probe enables the detection of bovine serum albumin (BSA) biomolecule with a detection limit of 19.35 μM. The demonstrated fiber probe here provides a potential strategy to integrate plasmonic nanostructure on the fiber facet with excellent sensing performance, which has a unique application prospect in the detection of remote, in situ, and in vivo invasion.

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Section: Introductionmentioning

confidence: 99%

Plasmonic Resonance Coupling of Nanodisk Array/Thin Film on the Optical Fiber Tip for Integrated and Miniaturized Sensing Detection

Wei

et al. 2023

Sensors

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“…In contrast, chemical immobilization of gold nanoparticles (AuNPs) on the end face of an optical fiber results on a much simpler and cost-effective process. Kajikawa and co-workers described this method for the first time 32 , and it has been widely used in the last decade for many biosensing applications 33 – 40 . This method consists in the attachment of colloidal AuNPs to a self assembled monolayer (SAM) by immersion of the functionalized fiber facet in a AuNPs suspension, which requires less equipment and is more versatile (it can be used with any type of NPs).…”

Section: Introductionmentioning

confidence: 99%

A method for the controllable fabrication of optical fiber-based localized surface plasmon resonance sensors

Calatayud-Sánchez

Ortega-Gomez

Barroso

et al. 2022

Sci Rep

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Optical fiber-based Localized Surface Plasmon Resonance (OF-LSPR) biosensors have emerged as an ultra-sensitive miniaturized tool for a great variety of applications. Their fabrication by the chemical immobilization of gold nanoparticles (AuNPs) on the optic fiber end face is a simple and versatile method. However, it can render poor reproducibility given the number of parameters that influence the binding of the AuNPs. In order to develop a method to obtain OF-LSPR sensors with high reproducibility, we studied the effect that factors such as temperature, AuNPs concentration, fiber core size and time of immersion had on the number and aggregation of AuNPs on the surface of the fibers and their resonance signal. Our method consisted in controlling the deposition of a determined AuNPs density on the tip of the fiber by measuring its LSPR signal (or plasmonic signal, Sp) in real-time. Sensors created thus were used to measure changes in the refractive index of their surroundings and the results showed that, as the number of AuNPs on the probes increased, the changes in the Sp maximum values were ever lower but the wavelength shifts were higher. These results highlighted the relevance of controlling the relationship between the sensor composition and its performance.

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An ultrasensitive J-shaped optical fiber LSPR aptasensor for the detection of Helicobacter pylori

Ning,

Hu,

Zhou

et al. 2023

Analytica Chimica Acta

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Fabrication and measurement of a fiber optic localized surface plasmon resonance sensor chip for molecular diagnostics

Cited by 6 publications

References 46 publications

Plasmonic Resonance Coupling of Nanodisk Array/Thin Film on the Optical Fiber Tip for Integrated and Miniaturized Sensing Detection

Plasmonic Resonance Coupling of Nanodisk Array/Thin Film on the Optical Fiber Tip for Integrated and Miniaturized Sensing Detection

A method for the controllable fabrication of optical fiber-based localized surface plasmon resonance sensors

An ultrasensitive J-shaped optical fiber LSPR aptasensor for the detection of Helicobacter pylori

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