Fabrication of anti-bacterial cotton bandage using biologically synthesized nanoparticles for medical applications

Abstract

Recently the use of plant-derived extracts for the green synthesis of nanoparticles has drawn considerable attention. In the present study silver and copper nanoparticles were synthesized using extracts of Andrographis paniculata which is found to possess various pharmacological properties. The synthesized nanoparticles were characterized using UV spectroscopy, SEM with EDS, XRD, TEM and DLS. Furthermore, an attempt is made to impregnate these nanoparticles onto cotton bandages. The structure and morphology of silver nanoparticles impregnated onto the cotton bandages were confirmed by SEM. The anti-bacterial activity of cotton bandages loaded with silver and copper nanoparticles was tested against Escherichia coli , Bacillus cereus , and Staphylococcus aureus using a modified disc diffusion assay. The results indicate that the cotton bandages biofabricated with nanoparticles exhibited anti-bacterial activity in terms of zone of inhibition of growth of tested bacteria suggesting their usage as medical textiles in various biomedical applications for the prevention of infections. Hence, the nanoparticles impregnated cotton fibers can be applied for the development of masks, aprons, etc. to protect against bacterial penetration and as well to counteract the present situation of the world.

Enhancement of Antibacterial Silk Face Covering with the Biosynthesis of Silver Nanoparticles from Garcinia mangostana Linn. Peel and Andrographis paniculata Extract and a Bacterial Cellulose Filter

“…The analysis of the silver nanoparticle content on the surface of cotton fabric based on EDS is shown in Table 6 and Figure 5. The peak at 3 keV confirmed the presence of the silver nanoparticles [26]. The amounts of silver nanoparticles decreased from before washing (3.70%) to after 20 and 30 washing cycles (2.48% and 1.63%, respectively), representing a reduction of 32.97% and 55.95% after washing.…”

“…Andrographis paniculata or green chiretta is an annual plant whose entire above-ground parts (leaves, flowers, and stems) can be used as a medicinal plant to treat common cold and fever [26]. The active ingredients include andrographolide, neoandrographolide, isoandrographolide, and 14-deoxyandrographolide [27].…”

Biogenic synthesis of RICINUS COMMUNIS mediated iron and silver nanoparticles and its antibacterial and antifungal activity

“…Furthermore, the SPR band for silver nanoparticles obtained the absorbance peak at 430 nm, as reported in previous studies [ 14 ]. Similarly, Monika et al [ 4 ] reported that silver nanoparticles prepared using a plant extract exhibited a strong plasmon peak at 429 nm. The band intensity produced by silver nanoparticles was identified as a peak due to the surface plasmon resonance, which is an intrinsic property of metal band-based nanoparticles.…”

“…Nanoparticles have gained attention due to their unique morphological and physicochemical properties [ 3 ]. These metal nanoparticles possess strong inhibitory and antibacterial activity [ 4 ]. Iron nanoparticles have been widely applied in drug delivery and biomedical applications and possess toxicity against a broad spectrum of pathogenic bacteria and fungi [ 5 ].…”

Compressed Hydrogen-Induced Synthesis of Quaternary Trimethyl Chitosan-Silver Nanoparticles with Dual Antibacterial and Antifungal Activities

“…The emergence of antimicrobial resistance (AMR) pathogens complicates the treatment of bacterial and fungi infections, necessitating the development of novel approaches to address this global catastrophic threat . AMR has caused significant damage to numerous healthcare systems throughout the world, jeopardizing efforts to prevent and treat a variety of infectious diseases. , Starting from 2050, AMR might result in ten million deaths annually and could cost the entire world the approximate sum of 100.2 trillion US dollars .…”