Fabrication of biomimetic apatite coating on porous titanium and their osteointegration in femurs of dogs

Advances in Biomimetic Apatite Coating on Metal Implants

“…Similar to the previously described study, Habibovic et al found that the application of OCP coating on porous Ti6Al4V implants could improve its performance in bone healing process in femoral defects of goats (Habibovic et al, 2005). In a study, AA-or AH-pretreated porous titanium with biomimetic apatite coatings were hemi-transcortically implanted into the femurs of dogs for 2 months, and they showed excellent osteointegration with host bone (Zhao et al, 2010a). Yan et al investigated the effects of AH treatment, and bone-like apatite-formed on titanium after such treatment on the bone-bonding ability of Ti implants by implanted into the tibial metaphyses of mature rabbits.…”

(Ti, O)/Ti and (Ti, O, N)/Ti composite coatings fabricated via PIIID for the medical application of NiTi shape memory alloy

“…Absorption bands at 562 and 602 cm −1 were attributed to the OPO bending vibration of the PO 4 3− functional group and the absorption band at 874 cm −1 could arise from the bending vibration of CO 3 2− or PO stretching vibration of HPO 4 2− , which are characteristic of calcium‐deficient carbonated apatite (the “bone‐like apatite”), as CO 3 2− and HPO 4 2− groups substituted for the PO 4 3− group in the apatite lattice 19. In addition, the band at 1032 cm −1 was because of OPO stretching vibration of the PO 4 3− functional group, and the peaks at 1420 and 1458 cm −1 corresponded to the asymmetric stretching vibration of CO 3 2− 20. OH bending and stretching vibration of absorbed H 2 O resulted in the bands at 1637 and 3467 cm −1 , respectively 21.…”

Optimal Features of Porosity of Ti Alloys Considering their Bioactivity and Mechanical Properties

“…The porous titanium implants should match their mechanical properties, particularly elastic modulus and stiffness, to those of the surrounding bone and provide a favourable environment for bone ingrowth. It has been reported that the elastic modulus of titanium scaffold could be adjusted to match with that of a natural bone for eliminating the stress shielding by altering its porosity [58][59][60] as listed in Table 2. Although increased porosity and pore size facilitate bone ingrowth, the result is a reduction in mechanical properties, so the compromise in mechanical properties with increasing porosity should set up an upper limit to maximum porosity and pore size of the porous titanium implant.…”